A metal-drug self-delivery nanomedicine alleviates tumor immunosuppression to potentiate synergistic chemo/chemodynamic therapy against hepatocellular carcinoma

A metal-drug self-delivery nanomedicine alleviates tumor immunosuppression to potentiate synergistic chemo/chemodynamic therapy against hepatocellular carcinoma

ABSTRACT: Hepatocellular carcinoma (HCC) is the most common primary liver cancer with a poor prognosis. Chemotherapy is one of the first-line clinical therapeutic strategies for HCC. Still, the effectiveness of chemotherapy is hampered by the tumor immunosuppressive microenvironment and drug resista...

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Bibliographic Details
Main Authors: Chen Guo, Rui Dou, Linbang Wang, Jiayu Zhang, Xiaomeng Cai, Jiaruo Tang, Zhengyuan Huang, Xiaoguang Liu, Jun Chen, Hanqing Chen
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2025-07-01
Series:Fundamental Research
Subjects:
Hepatocellular carcinoma
Metal-drug self-delivery nanomedicine
Chemotherapy
Chemodynamic therapy
Immunosuppressive microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S2667325824005351
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