Autochthonous human case of Echinococcus ortleppi cystic echinococcosis in Brittany, Western part of France

Human cystic echinococcosis (CE) is a worldwide infection due to the larval stage of Echinococcus granulosus sensu lato, a taeniid tapeworm of canids. Identification of the causative agent at species level relies on molecular methods such as DNA sequencing or species-specific qPCR, which are rarely...

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Main Authors: Brice Autier, Marion Baldeyrou, Heithem Jeddou, Coralie Barrera, Jean-Pierre Gangneux
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Food and Waterborne Parasitology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405676625000113
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author Brice Autier
Marion Baldeyrou
Heithem Jeddou
Coralie Barrera
Jean-Pierre Gangneux
author_facet Brice Autier
Marion Baldeyrou
Heithem Jeddou
Coralie Barrera
Jean-Pierre Gangneux
author_sort Brice Autier
collection DOAJ
description Human cystic echinococcosis (CE) is a worldwide infection due to the larval stage of Echinococcus granulosus sensu lato, a taeniid tapeworm of canids. Identification of the causative agent at species level relies on molecular methods such as DNA sequencing or species-specific qPCR, which are rarely used for routine case management. Among the different species within the E. granulosus complex, Echinococcus ortleppi (E. granulosus genotype G5 former “cattle strain”) has been reported in only 19 human cases worldwide, including 3 in France. We report the 20th case of E. ortleppi cystic echinococcosis, which is an French autochthonous case of a patient without usual risk factors for CE, and living in an area not known to be endemic for E. ortleppi. This case highlights that medical community should be aware of the benefits from molecular epidemiology in understanding the landscape of parasitic diseases.
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issn 2405-6766
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publishDate 2025-06-01
publisher Elsevier
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series Food and Waterborne Parasitology
spelling doaj-art-c032c07ee8934f96aded877fd0b015e92025-08-20T02:32:33ZengElsevierFood and Waterborne Parasitology2405-67662025-06-0139e0026410.1016/j.fawpar.2025.e00264Autochthonous human case of Echinococcus ortleppi cystic echinococcosis in Brittany, Western part of FranceBrice Autier0Marion Baldeyrou1Heithem Jeddou2Coralie Barrera3Jean-Pierre Gangneux4Université de Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S, 1085 Rennes, France; Corresponding author at: Laboratoire de Parasitologie-Mycologie médicale, CHU Rennes – site Pontchaillou, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9, France.Service de Maladies Infectieuses et Réanimation Médicale, CHU de Rennes, Rennes, FranceService de chirurgie hépatobiliaire et digestive, CHU Rennes, Rennes, FranceDepartment of Parasitology-Mycology, National Reference Centre for Echinococcoses, University Hospital of Besançon, France; UMR CNRS 6249 Laboratoire Chrono-environnement, Université Bourgogne-Franche-Comté, Besançon, FranceUniversité de Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S, 1085 Rennes, FranceHuman cystic echinococcosis (CE) is a worldwide infection due to the larval stage of Echinococcus granulosus sensu lato, a taeniid tapeworm of canids. Identification of the causative agent at species level relies on molecular methods such as DNA sequencing or species-specific qPCR, which are rarely used for routine case management. Among the different species within the E. granulosus complex, Echinococcus ortleppi (E. granulosus genotype G5 former “cattle strain”) has been reported in only 19 human cases worldwide, including 3 in France. We report the 20th case of E. ortleppi cystic echinococcosis, which is an French autochthonous case of a patient without usual risk factors for CE, and living in an area not known to be endemic for E. ortleppi. This case highlights that medical community should be aware of the benefits from molecular epidemiology in understanding the landscape of parasitic diseases.http://www.sciencedirect.com/science/article/pii/S2405676625000113EchinococcosisEchinococcus granulosusCestode
spellingShingle Brice Autier
Marion Baldeyrou
Heithem Jeddou
Coralie Barrera
Jean-Pierre Gangneux
Autochthonous human case of Echinococcus ortleppi cystic echinococcosis in Brittany, Western part of France
Food and Waterborne Parasitology
Echinococcosis
Echinococcus granulosus
Cestode
title Autochthonous human case of Echinococcus ortleppi cystic echinococcosis in Brittany, Western part of France
title_full Autochthonous human case of Echinococcus ortleppi cystic echinococcosis in Brittany, Western part of France
title_fullStr Autochthonous human case of Echinococcus ortleppi cystic echinococcosis in Brittany, Western part of France
title_full_unstemmed Autochthonous human case of Echinococcus ortleppi cystic echinococcosis in Brittany, Western part of France
title_short Autochthonous human case of Echinococcus ortleppi cystic echinococcosis in Brittany, Western part of France
title_sort autochthonous human case of echinococcus ortleppi cystic echinococcosis in brittany western part of france
topic Echinococcosis
Echinococcus granulosus
Cestode
url http://www.sciencedirect.com/science/article/pii/S2405676625000113
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