Summary of discussions from the 2022 OECD CRP-sponsored conference on innovating microbial pesticide testing

Abstract Microbial pesticides are a class of biopesticide that includes microorganisms, such as bacteria, fungi, viruses, and protozoa, that are applied for pest control. Mammalian (human health) and non-target organism hazard testing are required to support registrations of microbial pesticides; ho...

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Main Authors: Magdalini Sachana, Patience Browne, Domenico Deserio, Emily Hopwood, Eric Liégeois, Geoff Sinclair
Format: Article
Language:English
Published: SpringerOpen 2025-03-01
Series:Environmental Sciences Europe
Subjects:
Online Access:https://doi.org/10.1186/s12302-025-01085-x
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author Magdalini Sachana
Patience Browne
Domenico Deserio
Emily Hopwood
Eric Liégeois
Geoff Sinclair
author_facet Magdalini Sachana
Patience Browne
Domenico Deserio
Emily Hopwood
Eric Liégeois
Geoff Sinclair
author_sort Magdalini Sachana
collection DOAJ
description Abstract Microbial pesticides are a class of biopesticide that includes microorganisms, such as bacteria, fungi, viruses, and protozoa, that are applied for pest control. Mammalian (human health) and non-target organism hazard testing are required to support registrations of microbial pesticides; however, developers and regulators of microbial pesticides face both new and old challenges for testing. New challenges include how to design or adapt new approach methodologies (NAMs), typically developed for chemicals, to mammalian health testing for microbial pesticides. Older challenges involve need for improved guidance for hazard testing with non-target organisms. Both are viewed as potential barriers to the development and adoption of microbial pesticides, which are potential alternatives to chemical pesticides. The 2022 conference, Innovating Microbial Pesticide Testing (hereafter, “the Conference”), sponsored by the Organisation for Economic Cooperation and Development (OECD) Cooperative Research Program (CRP), brought together experts on these topics from academic, industry, government, and non-governmental organizations to discuss the above challenges and establish plans to address them. Speakers presented on their perspectives of the challenges and potential solutions, which informed and guided panel discussions. This paper summarizes the contributions from presentations and panel discussions toward the conference conclusions and resulting workplans.
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spelling doaj-art-c027e7fbdbda4ba4a486ca6767fb77c72025-08-20T02:56:06ZengSpringerOpenEnvironmental Sciences Europe2190-47152025-03-0137111310.1186/s12302-025-01085-xSummary of discussions from the 2022 OECD CRP-sponsored conference on innovating microbial pesticide testingMagdalini Sachana0Patience Browne1Domenico Deserio2Emily Hopwood3Eric Liégeois4Geoff Sinclair5Organisation for Economic Co-Operation and Development (OECD), Environment Health and Safety DivisionOrganisation for Economic Co-Operation and Development (OECD), Environment Health and Safety DivisionDirectorate-General for Health and Food Safety, European CommissionHealth Canada, Pest Management Regulatory AgencyDirectorate-General for Health and Food Safety, European CommissionOffice of Pesticide Programs, U.S. Environmental Protection AgencyAbstract Microbial pesticides are a class of biopesticide that includes microorganisms, such as bacteria, fungi, viruses, and protozoa, that are applied for pest control. Mammalian (human health) and non-target organism hazard testing are required to support registrations of microbial pesticides; however, developers and regulators of microbial pesticides face both new and old challenges for testing. New challenges include how to design or adapt new approach methodologies (NAMs), typically developed for chemicals, to mammalian health testing for microbial pesticides. Older challenges involve need for improved guidance for hazard testing with non-target organisms. Both are viewed as potential barriers to the development and adoption of microbial pesticides, which are potential alternatives to chemical pesticides. The 2022 conference, Innovating Microbial Pesticide Testing (hereafter, “the Conference”), sponsored by the Organisation for Economic Cooperation and Development (OECD) Cooperative Research Program (CRP), brought together experts on these topics from academic, industry, government, and non-governmental organizations to discuss the above challenges and establish plans to address them. Speakers presented on their perspectives of the challenges and potential solutions, which informed and guided panel discussions. This paper summarizes the contributions from presentations and panel discussions toward the conference conclusions and resulting workplans.https://doi.org/10.1186/s12302-025-01085-xMicrobial pesticideHuman health risk assessmentNon-target organismPesticide hazard testingBiopesticidesNew approach methodologies
spellingShingle Magdalini Sachana
Patience Browne
Domenico Deserio
Emily Hopwood
Eric Liégeois
Geoff Sinclair
Summary of discussions from the 2022 OECD CRP-sponsored conference on innovating microbial pesticide testing
Environmental Sciences Europe
Microbial pesticide
Human health risk assessment
Non-target organism
Pesticide hazard testing
Biopesticides
New approach methodologies
title Summary of discussions from the 2022 OECD CRP-sponsored conference on innovating microbial pesticide testing
title_full Summary of discussions from the 2022 OECD CRP-sponsored conference on innovating microbial pesticide testing
title_fullStr Summary of discussions from the 2022 OECD CRP-sponsored conference on innovating microbial pesticide testing
title_full_unstemmed Summary of discussions from the 2022 OECD CRP-sponsored conference on innovating microbial pesticide testing
title_short Summary of discussions from the 2022 OECD CRP-sponsored conference on innovating microbial pesticide testing
title_sort summary of discussions from the 2022 oecd crp sponsored conference on innovating microbial pesticide testing
topic Microbial pesticide
Human health risk assessment
Non-target organism
Pesticide hazard testing
Biopesticides
New approach methodologies
url https://doi.org/10.1186/s12302-025-01085-x
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