Case report: Metastatic melanoma derived from a somatic-type malignant transformation of a mediastinal teratoma treated with immune checkpoint inhibitors

Case report: Metastatic melanoma derived from a somatic-type malignant transformation of a mediastinal teratoma treated with immune checkpoint inhibitors

The treatment of patients affected by a teratoma with somatic-type malignancy (STM) is challenging, since they are characterized by a poor prognosis, due to chemoresistance to standard cisplatin-based regimens. Only five more case reports were described for melanomatous STM and for which there are n...

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Bibliographic Details
Main Authors: Roberto Rosenfeld, Silvia Riondino, Giusy Parisi, Giovanni Maria Iannantuono, Rexhina Ajdhoni, Francesco Torino, Sabrina Mariotti, Mario Roselli
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Oncology
Subjects:
teratoma
germ cell tumors
somatic-type malignancy
immune checkpoint inhibitors
case report
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1417776/full
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