Six-Year Implants Follow-Up After Guided Bone Regeneration Using Autologous Tooth Graft: Innovative Biomaterial for Bone Regeneration Tooth Transformer<sup>®</sup>

Objectives: Recently, there has been great interest in teeth and their derivatives as suitable substrates for the treatment of alveolar bone defects. This retrospective study evaluates the clinical and radiographic outcomes of implants inserted in a site that underwent GBR procedure using a tooth de...

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Main Authors: Elio Minetti, Angelo Michele Inchingolo, Laura Ferrante, Grazia Marinelli, Francesco Inchingolo, Alessio Danilo Inchingolo, Andrea Palermo, Gianna Dipalma
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Journal of Functional Biomaterials
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Online Access:https://www.mdpi.com/2079-4983/16/5/172
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author Elio Minetti
Angelo Michele Inchingolo
Laura Ferrante
Grazia Marinelli
Francesco Inchingolo
Alessio Danilo Inchingolo
Andrea Palermo
Gianna Dipalma
author_facet Elio Minetti
Angelo Michele Inchingolo
Laura Ferrante
Grazia Marinelli
Francesco Inchingolo
Alessio Danilo Inchingolo
Andrea Palermo
Gianna Dipalma
author_sort Elio Minetti
collection DOAJ
description Objectives: Recently, there has been great interest in teeth and their derivatives as suitable substrates for the treatment of alveolar bone defects. This retrospective study evaluates the clinical and radiographic outcomes of implants inserted in a site that underwent GBR procedure using a tooth derivate material. Materials and methods: A total of 21 patients received a GBR using an autologous extracted tooth. Four months after the GBR techniques, the implants were inserted and were followed for an average of 5.28 + −1.10 years after loading. The X-ray was analyzed after a period of 63.36 + −13.2 months for a total follow-up period. Results: A total of 28 implants were inserted. All the implants were clinically functional after the follow-up period. The average bone loss from the X-ray images was 0.1208 + −0.1307. Conclusion: Within the limitations of this study, the use of a tooth as a graft using a tooth transformer device guarantees the production of bone and maintenance over time.
format Article
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institution DOAJ
issn 2079-4983
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publishDate 2025-05-01
publisher MDPI AG
record_format Article
series Journal of Functional Biomaterials
spelling doaj-art-c0123f34034f4fc59ed24676aec0a7982025-08-20T03:14:35ZengMDPI AGJournal of Functional Biomaterials2079-49832025-05-0116517210.3390/jfb16050172Six-Year Implants Follow-Up After Guided Bone Regeneration Using Autologous Tooth Graft: Innovative Biomaterial for Bone Regeneration Tooth Transformer<sup>®</sup>Elio Minetti0Angelo Michele Inchingolo1Laura Ferrante2Grazia Marinelli3Francesco Inchingolo4Alessio Danilo Inchingolo5Andrea Palermo6Gianna Dipalma7Department of Biomedical, Surgical and Dental Science, University of Milan, 20122 Milan, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70124 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70124 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70124 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70124 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70124 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Salento, 73100 Lecce, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70124 Bari, ItalyObjectives: Recently, there has been great interest in teeth and their derivatives as suitable substrates for the treatment of alveolar bone defects. This retrospective study evaluates the clinical and radiographic outcomes of implants inserted in a site that underwent GBR procedure using a tooth derivate material. Materials and methods: A total of 21 patients received a GBR using an autologous extracted tooth. Four months after the GBR techniques, the implants were inserted and were followed for an average of 5.28 + −1.10 years after loading. The X-ray was analyzed after a period of 63.36 + −13.2 months for a total follow-up period. Results: A total of 28 implants were inserted. All the implants were clinically functional after the follow-up period. The average bone loss from the X-ray images was 0.1208 + −0.1307. Conclusion: Within the limitations of this study, the use of a tooth as a graft using a tooth transformer device guarantees the production of bone and maintenance over time.https://www.mdpi.com/2079-4983/16/5/172autogenous dentin particulatebone regenerationdental biomaterialsgrow factorshigh-speed grinderlow-speed grinder
spellingShingle Elio Minetti
Angelo Michele Inchingolo
Laura Ferrante
Grazia Marinelli
Francesco Inchingolo
Alessio Danilo Inchingolo
Andrea Palermo
Gianna Dipalma
Six-Year Implants Follow-Up After Guided Bone Regeneration Using Autologous Tooth Graft: Innovative Biomaterial for Bone Regeneration Tooth Transformer<sup>®</sup>
Journal of Functional Biomaterials
autogenous dentin particulate
bone regeneration
dental biomaterials
grow factors
high-speed grinder
low-speed grinder
title Six-Year Implants Follow-Up After Guided Bone Regeneration Using Autologous Tooth Graft: Innovative Biomaterial for Bone Regeneration Tooth Transformer<sup>®</sup>
title_full Six-Year Implants Follow-Up After Guided Bone Regeneration Using Autologous Tooth Graft: Innovative Biomaterial for Bone Regeneration Tooth Transformer<sup>®</sup>
title_fullStr Six-Year Implants Follow-Up After Guided Bone Regeneration Using Autologous Tooth Graft: Innovative Biomaterial for Bone Regeneration Tooth Transformer<sup>®</sup>
title_full_unstemmed Six-Year Implants Follow-Up After Guided Bone Regeneration Using Autologous Tooth Graft: Innovative Biomaterial for Bone Regeneration Tooth Transformer<sup>®</sup>
title_short Six-Year Implants Follow-Up After Guided Bone Regeneration Using Autologous Tooth Graft: Innovative Biomaterial for Bone Regeneration Tooth Transformer<sup>®</sup>
title_sort six year implants follow up after guided bone regeneration using autologous tooth graft innovative biomaterial for bone regeneration tooth transformer sup r sup
topic autogenous dentin particulate
bone regeneration
dental biomaterials
grow factors
high-speed grinder
low-speed grinder
url https://www.mdpi.com/2079-4983/16/5/172
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