The inverse relationship between dietary anthocyanidins consumption and frailty: Findings from the National Health and Nutrition Examination Survey.
<h4>Objective</h4>This study investigates the association between dietary anthocyanidins consumption and the risk of frailty in the general adult population using data from the National Health and Nutrition Examination Survey (NHANES).<h4>Methods</h4>A cross-sectional analysi...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0328489 |
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| author | Xiaofeng Zhang Pengpeng Huang Zhenhua Jin Yanfei Wu |
| author_facet | Xiaofeng Zhang Pengpeng Huang Zhenhua Jin Yanfei Wu |
| author_sort | Xiaofeng Zhang |
| collection | DOAJ |
| description | <h4>Objective</h4>This study investigates the association between dietary anthocyanidins consumption and the risk of frailty in the general adult population using data from the National Health and Nutrition Examination Survey (NHANES).<h4>Methods</h4>A cross-sectional analysis of NHANES data was conducted, examining the relationship between dietary anthocyanidins intake and frailty risk. Dose-response relationships and subgroup analyses were performed to provide a comprehensive understanding of the associations.<h4>Results</h4>The results indicate a significant inverse relationship between the consumption of specific anthocyanidin types, including malvidin and delphinidin, as well as total anthocyanidins, and the odds of frailty. Particularly, individuals aged 41-60 years and males exhibited a notable protective effect of anthocyanidins against frailty. Dose-response analyses revealed a U-shaped relationship between total anthocyanidins intake and frailty risk, with an optimal consumption level of 33.322 mg per day.<h4>Conclusion</h4>This pioneering study emphasizes the potential protective role of dietary anthocyanidins in mitigating frailty, especially among middle-aged individuals and males. |
| format | Article |
| id | doaj-art-c00dd2dcbb0046039a514ca95f41d1dd |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-c00dd2dcbb0046039a514ca95f41d1dd2025-08-20T03:39:14ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01208e032848910.1371/journal.pone.0328489The inverse relationship between dietary anthocyanidins consumption and frailty: Findings from the National Health and Nutrition Examination Survey.Xiaofeng ZhangPengpeng HuangZhenhua JinYanfei Wu<h4>Objective</h4>This study investigates the association between dietary anthocyanidins consumption and the risk of frailty in the general adult population using data from the National Health and Nutrition Examination Survey (NHANES).<h4>Methods</h4>A cross-sectional analysis of NHANES data was conducted, examining the relationship between dietary anthocyanidins intake and frailty risk. Dose-response relationships and subgroup analyses were performed to provide a comprehensive understanding of the associations.<h4>Results</h4>The results indicate a significant inverse relationship between the consumption of specific anthocyanidin types, including malvidin and delphinidin, as well as total anthocyanidins, and the odds of frailty. Particularly, individuals aged 41-60 years and males exhibited a notable protective effect of anthocyanidins against frailty. Dose-response analyses revealed a U-shaped relationship between total anthocyanidins intake and frailty risk, with an optimal consumption level of 33.322 mg per day.<h4>Conclusion</h4>This pioneering study emphasizes the potential protective role of dietary anthocyanidins in mitigating frailty, especially among middle-aged individuals and males.https://doi.org/10.1371/journal.pone.0328489 |
| spellingShingle | Xiaofeng Zhang Pengpeng Huang Zhenhua Jin Yanfei Wu The inverse relationship between dietary anthocyanidins consumption and frailty: Findings from the National Health and Nutrition Examination Survey. PLoS ONE |
| title | The inverse relationship between dietary anthocyanidins consumption and frailty: Findings from the National Health and Nutrition Examination Survey. |
| title_full | The inverse relationship between dietary anthocyanidins consumption and frailty: Findings from the National Health and Nutrition Examination Survey. |
| title_fullStr | The inverse relationship between dietary anthocyanidins consumption and frailty: Findings from the National Health and Nutrition Examination Survey. |
| title_full_unstemmed | The inverse relationship between dietary anthocyanidins consumption and frailty: Findings from the National Health and Nutrition Examination Survey. |
| title_short | The inverse relationship between dietary anthocyanidins consumption and frailty: Findings from the National Health and Nutrition Examination Survey. |
| title_sort | inverse relationship between dietary anthocyanidins consumption and frailty findings from the national health and nutrition examination survey |
| url | https://doi.org/10.1371/journal.pone.0328489 |
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