Association of a pace of aging epigenetic clock with rate of cognitive decline in the Framingham Heart Study Offspring Cohort
Abstract INTRODUCTION The geroscience hypothesis proposes systemic biological aging is a root cause of cognitive decline. METHODS We analyzed Framingham Heart Study Offspring Cohort data (n = 2296; 46% male; baseline age M = 62, SD = 9, range = 25–101 y). We measured cognitive decline across two dec...
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| Main Authors: | Micah J. Savin, Haoyang Wang, Heming Pei, Allison E. Aiello, Stephanie Assuras, Avshalom Caspi, Terrie E. Moffitt, Peter A. Muenning, Calen P. Ryan, Baoyi Shi, Yaakov Stern, Karen Sugden, Linda Valeri, Daniel W. Belsky |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-10-01
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| Series: | Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/dad2.70038 |
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