Assessment of SOX2 performance as a marker for circulating cancer stem-like cells (CCSCs) identification in advanced breast cancer patients using CytoTrack system
Recent studies have highlighted that one of the main drivers for metastatic formation and resistance to the therapy are circulating tumor cells (CTCs) and cancer stem-like cells (CSCs). Measuring the CTCs has emerged as a non-invasive procedure for selecting the patients with higher risk of progress...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2025-08-01
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| Series: | Open Medicine |
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| Online Access: | https://doi.org/10.1515/med-2025-1265 |
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| author | Szostakowska-Rodzoś Małgorzata Fabisiewicz Anna Myśliwy Izabella Jagiełło-Gruszfeld Agnieszka Konieczna Aleksandra Grzybowska Ewa A. |
| author_facet | Szostakowska-Rodzoś Małgorzata Fabisiewicz Anna Myśliwy Izabella Jagiełło-Gruszfeld Agnieszka Konieczna Aleksandra Grzybowska Ewa A. |
| author_sort | Szostakowska-Rodzoś Małgorzata |
| collection | DOAJ |
| description | Recent studies have highlighted that one of the main drivers for metastatic formation and resistance to the therapy are circulating tumor cells (CTCs) and cancer stem-like cells (CSCs). Measuring the CTCs has emerged as a non-invasive procedure for selecting the patients with higher risk of progression/relapse. However, still there are no methods enabling the identification of stem-like phenotype of the CTCs. |
| format | Article |
| id | doaj-art-bffd855cd8984f748099d00f01df0afb |
| institution | Kabale University |
| issn | 2391-5463 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj-art-bffd855cd8984f748099d00f01df0afb2025-08-25T06:10:52ZengDe GruyterOpen Medicine2391-54632025-08-0120173010.1515/med-2025-1265Assessment of SOX2 performance as a marker for circulating cancer stem-like cells (CCSCs) identification in advanced breast cancer patients using CytoTrack systemSzostakowska-Rodzoś Małgorzata0Fabisiewicz Anna1Myśliwy Izabella2Jagiełło-Gruszfeld Agnieszka3Konieczna Aleksandra4Grzybowska Ewa A.5Department of Molecular and Translational Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Roentgena 5, 02-781, Warsaw, PolandDepartment of Molecular and Translational Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Roentgena 5, 02-781, Warsaw, PolandDepartment of Molecular and Translational Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Roentgena 5, 02-781, Warsaw, PolandOncological Clinic, Oncological Mazovian Hospital, Warsaw, PolandDepartment of Breast Cancer and Reconstructive Surgery, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, PolandDepartment of Molecular and Translational Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Roentgena 5, 02-781, Warsaw, PolandRecent studies have highlighted that one of the main drivers for metastatic formation and resistance to the therapy are circulating tumor cells (CTCs) and cancer stem-like cells (CSCs). Measuring the CTCs has emerged as a non-invasive procedure for selecting the patients with higher risk of progression/relapse. However, still there are no methods enabling the identification of stem-like phenotype of the CTCs.https://doi.org/10.1515/med-2025-1265circulating tumor cellssox2cancer stem cellsbreast cancercytotrackliquid biopsy |
| spellingShingle | Szostakowska-Rodzoś Małgorzata Fabisiewicz Anna Myśliwy Izabella Jagiełło-Gruszfeld Agnieszka Konieczna Aleksandra Grzybowska Ewa A. Assessment of SOX2 performance as a marker for circulating cancer stem-like cells (CCSCs) identification in advanced breast cancer patients using CytoTrack system Open Medicine circulating tumor cells sox2 cancer stem cells breast cancer cytotrack liquid biopsy |
| title | Assessment of SOX2 performance as a marker for circulating cancer stem-like cells (CCSCs) identification in advanced breast cancer patients using CytoTrack system |
| title_full | Assessment of SOX2 performance as a marker for circulating cancer stem-like cells (CCSCs) identification in advanced breast cancer patients using CytoTrack system |
| title_fullStr | Assessment of SOX2 performance as a marker for circulating cancer stem-like cells (CCSCs) identification in advanced breast cancer patients using CytoTrack system |
| title_full_unstemmed | Assessment of SOX2 performance as a marker for circulating cancer stem-like cells (CCSCs) identification in advanced breast cancer patients using CytoTrack system |
| title_short | Assessment of SOX2 performance as a marker for circulating cancer stem-like cells (CCSCs) identification in advanced breast cancer patients using CytoTrack system |
| title_sort | assessment of sox2 performance as a marker for circulating cancer stem like cells ccscs identification in advanced breast cancer patients using cytotrack system |
| topic | circulating tumor cells sox2 cancer stem cells breast cancer cytotrack liquid biopsy |
| url | https://doi.org/10.1515/med-2025-1265 |
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