Lupus pernio vs. lupic perniosis: A case report

Abstract Introduction: Systemic lupus erythematosus (SLE) is an autoimmune disease that is difficult to diagnose due to the wide array of signs and symptoms it displays that may be associated to multiple clinical conditions,  including perniosis (a rare inflammatory condition), lupus pernio (a ma...

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Main Authors: Doris Juliana Parra-Sepúlveda, Laura Catalina Urueña-Betancourt, Julián Felipe Porras-Villamil, Nadia Katherine Ríos-Camargo
Format: Article
Language:English
Published: Universidad Nacional de Colombia 2023-01-01
Series:Case Reports
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Online Access:https://revistas.unal.edu.co/index.php/care/article/view/92970
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Summary:Abstract Introduction: Systemic lupus erythematosus (SLE) is an autoimmune disease that is difficult to diagnose due to the wide array of signs and symptoms it displays that may be associated to multiple clinical conditions,  including perniosis (a rare inflammatory condition), lupus pernio (a manifestation of sarcoidosis), and lupus perniosis (a form of SLE), which can be easily mistaken. Case description: A 29-year-old Colombian mestizo woman with no family history of autoimmune, inflammatory or cutaneous diseases was diagnosed with SLE after ruling out several differential diagnoses. Although the patient presented with features of lupus pernioticus (lupus perniosis), it was established that she had lupus pernio, a type of sarcoidosis. The patient was given the indicated treatment, which led to an improvement in her quality of life. Conclusion: Based on the epidemiology, clinical history and histopathologic findings, it was possible to establish that the patient presented with lupus perniosis and not lupus pernio. In that regard, considering that these three conditions (perniosis, lupus pernio and lupic perniosis) can be easily confused, the present case highlights the importance of a thorough clinical evaluation and precise use of diagnostic terms, because these are three different conditions despite their similar names.
ISSN:2462-8522