In vitro, genomic characterization and pre-clinical evaluation of a new thermostable lytic Obolenskvirus phage formulated as a hydrogel against carbapenem-resistant Acinetobacter baumannii

In vitro, genomic characterization and pre-clinical evaluation of a new thermostable lytic Obolenskvirus phage formulated as a hydrogel against carbapenem-resistant Acinetobacter baumannii

Abstract The urgent threat of carbapenem-resistant Acinetobacter baumannii (CRAB) necessitates the development of new antimicrobial strategies. Bacteriophage (phage) therapy is one of the most promising alternative strategies that can be implemented to combat multidrug-resistant (MDR) bacterial infe...

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Bibliographic Details
Main Authors: Mahmoud M. Sherif, Neveen A. Abdelaziz, Mohammad Y. Alshahrani, Sarra E. Saleh, Khaled M. Aboshanab
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
CRAB
Acinetobacter baumannii
Phage
Molecular analysis
Hydrogel
Thermal animal model
Online Access:https://doi.org/10.1038/s41598-025-99788-x
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https://doi.org/10.1038/s41598-025-99788-x

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