A case of amyloid light amyloidosis involving multiorgan with hepatomegaly as the main manifestation

Amyloid light (AL) amyloidosis, also known as primary systemic amyloidosis, is a protein conformation disease, and is a clinical syndrome of functional failure of affected organs due to abnormal folding and deposition of insoluble fibrin in the extracellular region of organs or tissues. The diagnosi...

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Main Authors: Ya-Nan CHEN, Jia-Long LIU, Yi-Zhang LI, Ji-Xia ZHANG, Xian-Yan SHI, Jing LIU
Format: Article
Language:zho
Published: Editorial Office of New Medicine 2023-08-01
Series:Yixue xinzhi zazhi
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Online Access:https://yxxz.whuznhmedj.com/futureApi/storage/attach/2308/f2cqkUDC8STeHiQiEMfgyLPId0oQtRXyAYTQQLGe.pdf
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author Ya-Nan CHEN
Jia-Long LIU
Yi-Zhang LI
Ji-Xia ZHANG
Xian-Yan SHI
Jing LIU
author_facet Ya-Nan CHEN
Jia-Long LIU
Yi-Zhang LI
Ji-Xia ZHANG
Xian-Yan SHI
Jing LIU
author_sort Ya-Nan CHEN
collection DOAJ
description Amyloid light (AL) amyloidosis, also known as primary systemic amyloidosis, is a protein conformation disease, and is a clinical syndrome of functional failure of affected organs due to abnormal folding and deposition of insoluble fibrin in the extracellular region of organs or tissues. The diagnosis of AL-type amyloidosis is challenging because of its low incidence and complex clinical manifestations, and cases of multiple organ involvement are even rarer. We reported a case of AL-type amyloidosis with multiple organ involvement in order to provide refference for related diagnosis, treatment and prognosis.
format Article
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issn 1004-5511
language zho
publishDate 2023-08-01
publisher Editorial Office of New Medicine
record_format Article
series Yixue xinzhi zazhi
spelling doaj-art-bff432fb98d14d9cb71b14ff1fcd0a672025-08-20T02:00:13ZzhoEditorial Office of New MedicineYixue xinzhi zazhi1004-55112023-08-0133428529010.12173/j.issn.1004-5511.2022090546404A case of amyloid light amyloidosis involving multiorgan with hepatomegaly as the main manifestationYa-Nan CHENJia-Long LIUYi-Zhang LIJi-Xia ZHANGXian-Yan SHIJing LIUAmyloid light (AL) amyloidosis, also known as primary systemic amyloidosis, is a protein conformation disease, and is a clinical syndrome of functional failure of affected organs due to abnormal folding and deposition of insoluble fibrin in the extracellular region of organs or tissues. The diagnosis of AL-type amyloidosis is challenging because of its low incidence and complex clinical manifestations, and cases of multiple organ involvement are even rarer. We reported a case of AL-type amyloidosis with multiple organ involvement in order to provide refference for related diagnosis, treatment and prognosis.https://yxxz.whuznhmedj.com/futureApi/storage/attach/2308/f2cqkUDC8STeHiQiEMfgyLPId0oQtRXyAYTQQLGe.pdfamyloidosislight chain amyloidosismultiple organ involvement
spellingShingle Ya-Nan CHEN
Jia-Long LIU
Yi-Zhang LI
Ji-Xia ZHANG
Xian-Yan SHI
Jing LIU
A case of amyloid light amyloidosis involving multiorgan with hepatomegaly as the main manifestation
Yixue xinzhi zazhi
amyloidosis
light chain amyloidosis
multiple organ involvement
title A case of amyloid light amyloidosis involving multiorgan with hepatomegaly as the main manifestation
title_full A case of amyloid light amyloidosis involving multiorgan with hepatomegaly as the main manifestation
title_fullStr A case of amyloid light amyloidosis involving multiorgan with hepatomegaly as the main manifestation
title_full_unstemmed A case of amyloid light amyloidosis involving multiorgan with hepatomegaly as the main manifestation
title_short A case of amyloid light amyloidosis involving multiorgan with hepatomegaly as the main manifestation
title_sort case of amyloid light amyloidosis involving multiorgan with hepatomegaly as the main manifestation
topic amyloidosis
light chain amyloidosis
multiple organ involvement
url https://yxxz.whuznhmedj.com/futureApi/storage/attach/2308/f2cqkUDC8STeHiQiEMfgyLPId0oQtRXyAYTQQLGe.pdf
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