Variability in HOMA-IR, Lipoprotein Profile and Selected Hormones in Young Active Men
Resistance to insulin actions is contributing to many metabolic disturbances. Such factors as age, sex, nutrition, body fat, and physical activity determine body insulin resistance. Present study attempted to asses insulin resistance and its metabolic effects with respect to energy intake in young,...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2013/412764 |
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| author | Anna Keska Grazyna Lutoslawska Anna Czajkowska Joanna Tkaczyk Krzysztof Mazurek |
| author_facet | Anna Keska Grazyna Lutoslawska Anna Czajkowska Joanna Tkaczyk Krzysztof Mazurek |
| author_sort | Anna Keska |
| collection | DOAJ |
| description | Resistance to insulin actions is contributing to many metabolic disturbances. Such factors as age, sex, nutrition, body fat, and physical activity determine body insulin resistance. Present study attempted to asses insulin resistance and its metabolic effects with respect to energy intake in young, lean, and active men. A total of 87 men aged 18–23 participated in the study. Plasma levels of glucose, insulin, lipoproteins, cortisol, and TSH were determined. Insulin resistance was expressed as Homeostasis Model Assessment for Insulin Resistance (HOMA-IR) and calculated using homeostatic model. The median value of HOMA-IR (1.344) was used to divide subjects into two groups. Men did not differ in anthropometric parameters, daily physical activity, and plasma TSH and cortisol levels. However, in men with higher HOMA-IR significantly lower daily energy intake was observed concomitantly with higher TG, TC, and HDL-C concentrations in plasma versus their counterparts with lower HOMA-IR. Exclusively in subjects with higher HOMA-IR significant and positive correlation was noted between HOMA-IR and TC and LDL-C. We concluded that despite a normal body weight and physical activity, a subset of young men displayed unfavorable changes in insulin sensitivity and lipid profile, probably due to insufficient energy intake. |
| format | Article |
| id | doaj-art-bfdd423ca3d247b49709ec8364fc5d72 |
| institution | OA Journals |
| issn | 1537-744X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-bfdd423ca3d247b49709ec8364fc5d722025-08-20T02:19:26ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/412764412764Variability in HOMA-IR, Lipoprotein Profile and Selected Hormones in Young Active MenAnna Keska0Grazyna Lutoslawska1Anna Czajkowska2Joanna Tkaczyk3Krzysztof Mazurek4Department of Biochemistry and Biology, Józef Pilsudski University of Physical Education, P.O. Box 55, 01-968 Warsaw 45, PolandDepartment of Biochemistry and Biology, Józef Pilsudski University of Physical Education, P.O. Box 55, 01-968 Warsaw 45, PolandDepartment of Physiology, Józef Pilsudski University of Physical Education, P.O. Box 55, 01-968 Warsaw 45, PolandDepartment of Biochemistry and Biology, Józef Pilsudski University of Physical Education, P.O. Box 55, 01-968 Warsaw 45, PolandDepartment of Sports Medicine, Józef Pilsudski University of Physical Education, P.O. Box 55, 01-968 Warsaw 45, PolandResistance to insulin actions is contributing to many metabolic disturbances. Such factors as age, sex, nutrition, body fat, and physical activity determine body insulin resistance. Present study attempted to asses insulin resistance and its metabolic effects with respect to energy intake in young, lean, and active men. A total of 87 men aged 18–23 participated in the study. Plasma levels of glucose, insulin, lipoproteins, cortisol, and TSH were determined. Insulin resistance was expressed as Homeostasis Model Assessment for Insulin Resistance (HOMA-IR) and calculated using homeostatic model. The median value of HOMA-IR (1.344) was used to divide subjects into two groups. Men did not differ in anthropometric parameters, daily physical activity, and plasma TSH and cortisol levels. However, in men with higher HOMA-IR significantly lower daily energy intake was observed concomitantly with higher TG, TC, and HDL-C concentrations in plasma versus their counterparts with lower HOMA-IR. Exclusively in subjects with higher HOMA-IR significant and positive correlation was noted between HOMA-IR and TC and LDL-C. We concluded that despite a normal body weight and physical activity, a subset of young men displayed unfavorable changes in insulin sensitivity and lipid profile, probably due to insufficient energy intake.http://dx.doi.org/10.1155/2013/412764 |
| spellingShingle | Anna Keska Grazyna Lutoslawska Anna Czajkowska Joanna Tkaczyk Krzysztof Mazurek Variability in HOMA-IR, Lipoprotein Profile and Selected Hormones in Young Active Men The Scientific World Journal |
| title | Variability in HOMA-IR, Lipoprotein Profile and Selected Hormones in Young Active Men |
| title_full | Variability in HOMA-IR, Lipoprotein Profile and Selected Hormones in Young Active Men |
| title_fullStr | Variability in HOMA-IR, Lipoprotein Profile and Selected Hormones in Young Active Men |
| title_full_unstemmed | Variability in HOMA-IR, Lipoprotein Profile and Selected Hormones in Young Active Men |
| title_short | Variability in HOMA-IR, Lipoprotein Profile and Selected Hormones in Young Active Men |
| title_sort | variability in homa ir lipoprotein profile and selected hormones in young active men |
| url | http://dx.doi.org/10.1155/2013/412764 |
| work_keys_str_mv | AT annakeska variabilityinhomairlipoproteinprofileandselectedhormonesinyoungactivemen AT grazynalutoslawska variabilityinhomairlipoproteinprofileandselectedhormonesinyoungactivemen AT annaczajkowska variabilityinhomairlipoproteinprofileandselectedhormonesinyoungactivemen AT joannatkaczyk variabilityinhomairlipoproteinprofileandselectedhormonesinyoungactivemen AT krzysztofmazurek variabilityinhomairlipoproteinprofileandselectedhormonesinyoungactivemen |