Olfactory dysfunction in Alzheimer’s disease
Yong-ming Zou, Da Lu, Li-ping Liu, Hui-hong Zhang, Yu-ying Zhou Department of Neurology, Tianjin Huanhu Hospital, Tianjin, People’s Republic of China Abstract: Alzheimer’s disease (AD) is a common neurodegenerative disorder with the earliest clinical symptom of olfactor...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2016-04-01
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| Series: | Neuropsychiatric Disease and Treatment |
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| Online Access: | https://www.dovepress.com/olfactory-dysfunction-in-alzheimerrsquos-disease-peer-reviewed-fulltext-article-NDT |
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| author | Zou Y Lu D Liu L Zhang H Zhou Y |
| author_facet | Zou Y Lu D Liu L Zhang H Zhou Y |
| author_sort | Zou Y |
| collection | DOAJ |
| description | Yong-ming Zou, Da Lu, Li-ping Liu, Hui-hong Zhang, Yu-ying Zhou Department of Neurology, Tianjin Huanhu Hospital, Tianjin, People’s Republic of China Abstract: Alzheimer’s disease (AD) is a common neurodegenerative disorder with the earliest clinical symptom of olfactory dysfunction, which is a potential clinical marker for AD severity and progression. However, many questions remain unanswered. This article reviews relevant research on olfactory dysfunction in AD and evaluates the predictive value of olfactory dysfunction for the epidemiological, pathophysiological, and clinical features of AD, as well as for the conversion of cognitive impairment to AD. We summarize problems of existing studies and provide a useful reference for further studies in AD olfactory dysfunction and for clinical applications of olfactory testing. Keywords: olfactory dysfunction, Alzheimer’s disease, olfactory testing, progress |
| format | Article |
| id | doaj-art-bfda3d9a38884860b6da4daaa0273d82 |
| institution | Kabale University |
| issn | 1178-2021 |
| language | English |
| publishDate | 2016-04-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Neuropsychiatric Disease and Treatment |
| spelling | doaj-art-bfda3d9a38884860b6da4daaa0273d822025-08-20T03:27:01ZengDove Medical PressNeuropsychiatric Disease and Treatment1178-20212016-04-01Volume 12Issue 186987526444Olfactory dysfunction in Alzheimer’s diseaseZou Y0Lu DLiu LZhang HZhou Y1Department of NeurologyDepartment of NeurologyYong-ming Zou, Da Lu, Li-ping Liu, Hui-hong Zhang, Yu-ying Zhou Department of Neurology, Tianjin Huanhu Hospital, Tianjin, People’s Republic of China Abstract: Alzheimer’s disease (AD) is a common neurodegenerative disorder with the earliest clinical symptom of olfactory dysfunction, which is a potential clinical marker for AD severity and progression. However, many questions remain unanswered. This article reviews relevant research on olfactory dysfunction in AD and evaluates the predictive value of olfactory dysfunction for the epidemiological, pathophysiological, and clinical features of AD, as well as for the conversion of cognitive impairment to AD. We summarize problems of existing studies and provide a useful reference for further studies in AD olfactory dysfunction and for clinical applications of olfactory testing. Keywords: olfactory dysfunction, Alzheimer’s disease, olfactory testing, progresshttps://www.dovepress.com/olfactory-dysfunction-in-alzheimerrsquos-disease-peer-reviewed-fulltext-article-NDTolfactory dysfunctionAlzheimer’s diseaseolfactory testingprogress |
| spellingShingle | Zou Y Lu D Liu L Zhang H Zhou Y Olfactory dysfunction in Alzheimer’s disease Neuropsychiatric Disease and Treatment olfactory dysfunction Alzheimer’s disease olfactory testing progress |
| title | Olfactory dysfunction in Alzheimer’s disease |
| title_full | Olfactory dysfunction in Alzheimer’s disease |
| title_fullStr | Olfactory dysfunction in Alzheimer’s disease |
| title_full_unstemmed | Olfactory dysfunction in Alzheimer’s disease |
| title_short | Olfactory dysfunction in Alzheimer’s disease |
| title_sort | olfactory dysfunction in alzheimer amp rsquo s disease |
| topic | olfactory dysfunction Alzheimer’s disease olfactory testing progress |
| url | https://www.dovepress.com/olfactory-dysfunction-in-alzheimerrsquos-disease-peer-reviewed-fulltext-article-NDT |
| work_keys_str_mv | AT zouy olfactorydysfunctioninalzheimeramprsquosdisease AT lud olfactorydysfunctioninalzheimeramprsquosdisease AT liul olfactorydysfunctioninalzheimeramprsquosdisease AT zhangh olfactorydysfunctioninalzheimeramprsquosdisease AT zhouy olfactorydysfunctioninalzheimeramprsquosdisease |