Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection

Purpose. To report on a case of reactivation of acute retinal necrosis following SARS-CoV-2 infection. Methods. Observational case report. Observations. A 32-year-old female with a distant history of left retinal detachment secondary to necrotizing herpetic retinitis complained of right-eye vision l...

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Main Authors: Monica P. Gonzalez, Radames Rios, Mariella Pappaterra, Miguel Hernandez, Allison Toledo, Carmen Santos, Andres Emanuelli, Shree K. Kurup, Armando L. Oliver
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2021/7336488
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author Monica P. Gonzalez
Radames Rios
Mariella Pappaterra
Miguel Hernandez
Allison Toledo
Carmen Santos
Andres Emanuelli
Shree K. Kurup
Armando L. Oliver
author_facet Monica P. Gonzalez
Radames Rios
Mariella Pappaterra
Miguel Hernandez
Allison Toledo
Carmen Santos
Andres Emanuelli
Shree K. Kurup
Armando L. Oliver
author_sort Monica P. Gonzalez
collection DOAJ
description Purpose. To report on a case of reactivation of acute retinal necrosis following SARS-CoV-2 infection. Methods. Observational case report. Observations. A 32-year-old female with a distant history of left retinal detachment secondary to necrotizing herpetic retinitis complained of right-eye vision loss, pain, redness, and photophobia. An ophthalmological examination revealed findings consistent with acute retinal necrosis of the right eye. A polymerase chain reaction (PCR) analysis of the right vitreous was positive for herpes simplex virus type 2 (HSV-2). A coronavirus disease 2019 (COVID-19) screening test using reverse transcriptase- (RT-) PCR was positive for SARS-CoV-2 RNA. Conclusions. Our case suggests that COVID-19 may cause a latent HSV infection to reactivate, causing contralateral involvement in patients with a prior history of HSV-associated acute retinal necrosis.
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2090-6730
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publishDate 2021-01-01
publisher Wiley
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series Case Reports in Ophthalmological Medicine
spelling doaj-art-bfd5218ce3cb41cd8b514f582968058d2025-08-20T02:19:26ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302021-01-01202110.1155/2021/73364887336488Reactivation of Acute Retinal Necrosis following SARS-CoV-2 InfectionMonica P. Gonzalez0Radames Rios1Mariella Pappaterra2Miguel Hernandez3Allison Toledo4Carmen Santos5Andres Emanuelli6Shree K. Kurup7Armando L. Oliver8University of Puerto Rico, Medical Sciences Campus, Department of Ophthalmology, Paseo Dr. Jose Celso Barbosa, San Juan 00921, USAUniversity of Puerto Rico, Medical Sciences Campus, Department of Ophthalmology, Paseo Dr. Jose Celso Barbosa, San Juan 00921, USAUniversity of Puerto Rico, Medical Sciences Campus, Department of Ophthalmology, Paseo Dr. Jose Celso Barbosa, San Juan 00921, USAPonce Health Sciences University School of Medicine, 388 Zona Industrial Reparada 2, Ponce, PR 00716, USAEmanuelli Research and Development Center, 452 Dr R Rivera Aulet Avenue, Suite 45 Arecibo, PR 00612-4368, USAUniversity of Puerto Rico, Medical Sciences Campus, Department of Ophthalmology, Paseo Dr. Jose Celso Barbosa, San Juan 00921, USAUniversity of Puerto Rico, Medical Sciences Campus, Department of Ophthalmology, Paseo Dr. Jose Celso Barbosa, San Juan 00921, USAUniversity of Puerto Rico, Medical Sciences Campus, Department of Ophthalmology, Paseo Dr. Jose Celso Barbosa, San Juan 00921, USAUniversity of Puerto Rico, Medical Sciences Campus, Department of Ophthalmology, Paseo Dr. Jose Celso Barbosa, San Juan 00921, USAPurpose. To report on a case of reactivation of acute retinal necrosis following SARS-CoV-2 infection. Methods. Observational case report. Observations. A 32-year-old female with a distant history of left retinal detachment secondary to necrotizing herpetic retinitis complained of right-eye vision loss, pain, redness, and photophobia. An ophthalmological examination revealed findings consistent with acute retinal necrosis of the right eye. A polymerase chain reaction (PCR) analysis of the right vitreous was positive for herpes simplex virus type 2 (HSV-2). A coronavirus disease 2019 (COVID-19) screening test using reverse transcriptase- (RT-) PCR was positive for SARS-CoV-2 RNA. Conclusions. Our case suggests that COVID-19 may cause a latent HSV infection to reactivate, causing contralateral involvement in patients with a prior history of HSV-associated acute retinal necrosis.http://dx.doi.org/10.1155/2021/7336488
spellingShingle Monica P. Gonzalez
Radames Rios
Mariella Pappaterra
Miguel Hernandez
Allison Toledo
Carmen Santos
Andres Emanuelli
Shree K. Kurup
Armando L. Oliver
Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection
Case Reports in Ophthalmological Medicine
title Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection
title_full Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection
title_fullStr Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection
title_full_unstemmed Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection
title_short Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection
title_sort reactivation of acute retinal necrosis following sars cov 2 infection
url http://dx.doi.org/10.1155/2021/7336488
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