Naringin promotes osteoblast differentiation and ameliorates osteoporosis in ovariectomized mice

Naringin promotes osteoblast differentiation and ameliorates osteoporosis in ovariectomized mice

Abstract This study aimed to investigate the anti-osteoporotic mechanisms of naringin in osteoblasts and mice. In vitro, MC3T3-E1 cells were treated with naringin to detect cell proliferation, alkaline phosphatase (ALP) activity, and calcified nodule formation. Western blot was used to analyze the e...

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Bibliographic Details
Main Authors: Yubo Cui, Zhijun Yang, Guisong Yu, Jihui Hu, Dian Li, Xing Fu, Wenlong Yang, Fengyun Yang
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Osteoporosis
Wnt/β-catenin
Naringin
OVX
Online Access:https://doi.org/10.1038/s41598-025-97217-7
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