Drug-Induced Acute Dystonia After Sacubitril/Valsartan Combination
Adverse drug reaction by definition can be an unpleasant response due to a drug use that can adversely affect a person and may call for either treatment or withdrawal of the medication. We found classical dystonia in a young girl who presented with reduced systolic left ventricular function, had car...
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| Format: | Article |
| Language: | English |
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American College of Physicians
2024-02-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2023.0131 |
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| author | Prabhat Tewari Shantanu Pande Divya Arora |
| author_facet | Prabhat Tewari Shantanu Pande Divya Arora |
| author_sort | Prabhat Tewari |
| collection | DOAJ |
| description | Adverse drug reaction by definition can be an unpleasant response due to a drug use that can adversely affect a person and may call for either treatment or withdrawal of the medication. We found classical dystonia in a young girl who presented with reduced systolic left ventricular function, had cardiac surgery, and was prescribed sacubitril/valsartan combination for reversal of remodeling of the heart. The dystonia did not reoccur after stoppage of this combination. Although being an effective drug for heart failure with reduced ejection fraction, newer indications will need further assessment for the different dose regimen and adverse drug reactions. |
| format | Article |
| id | doaj-art-bfc267c22e8340e3bd6bef6e612bf576 |
| institution | OA Journals |
| issn | 2767-7664 |
| language | English |
| publishDate | 2024-02-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-bfc267c22e8340e3bd6bef6e612bf5762025-08-20T02:12:58ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642024-02-013210.7326/aimcc.2023.0131Drug-Induced Acute Dystonia After Sacubitril/Valsartan CombinationPrabhat Tewari0Shantanu Pande1Divya Arora21Department of Anesthesiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, Uttar Pradesh, India2Department of Cardiothoracic and Vascular Surgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, Uttar Pradesh, India1Department of Anesthesiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, Uttar Pradesh, IndiaAdverse drug reaction by definition can be an unpleasant response due to a drug use that can adversely affect a person and may call for either treatment or withdrawal of the medication. We found classical dystonia in a young girl who presented with reduced systolic left ventricular function, had cardiac surgery, and was prescribed sacubitril/valsartan combination for reversal of remodeling of the heart. The dystonia did not reoccur after stoppage of this combination. Although being an effective drug for heart failure with reduced ejection fraction, newer indications will need further assessment for the different dose regimen and adverse drug reactions.https://www.acpjournals.org/doi/10.7326/aimcc.2023.0131 |
| spellingShingle | Prabhat Tewari Shantanu Pande Divya Arora Drug-Induced Acute Dystonia After Sacubitril/Valsartan Combination Annals of Internal Medicine: Clinical Cases |
| title | Drug-Induced Acute Dystonia After Sacubitril/Valsartan Combination |
| title_full | Drug-Induced Acute Dystonia After Sacubitril/Valsartan Combination |
| title_fullStr | Drug-Induced Acute Dystonia After Sacubitril/Valsartan Combination |
| title_full_unstemmed | Drug-Induced Acute Dystonia After Sacubitril/Valsartan Combination |
| title_short | Drug-Induced Acute Dystonia After Sacubitril/Valsartan Combination |
| title_sort | drug induced acute dystonia after sacubitril valsartan combination |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2023.0131 |
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