Construction of an anaplastic thyroid cancer stratification signature to guide immune therapy selection and validation of the pivotal gene HLF through in vitro experiments

Construction of an anaplastic thyroid cancer stratification signature to guide immune therapy selection and validation of the pivotal gene HLF through in vitro experiments

IntroductionWhile most thyroid cancer patients have a favorable prognosis, anaplastic thyroid carcinoma (ATC) remains a particularly aggressive form with a median survival time of just five months. Conventional therapies offer limited benefits for this type of thyroid cancer. Our study aims to ident...

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Bibliographic Details
Main Authors: Li Pengping, Yin Kexin, Xie Yuwei, Sun Ke, Li Rongguo, Wang Zhenyu, Jin Haigang, Wang Shaowen, Huang Yuqing
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
anaplastic thyroid cancer (ATC)
T cell immunity
machine learning
prediction
model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1478904/full
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