Proteome-wide mendelian randomization identifies causal plasma proteins in interstitial lung disease

Proteome-wide mendelian randomization identifies causal plasma proteins in interstitial lung disease

Abstract Interstitial lung disease (ILD) has shown limited treatment advancements, with minimal exploration of circulating protein biomarkers causally linked to ILD and its subtypes beyond idiopathic pulmonary fibrosis (IPF). In this study, we aimed to identify potential drug targets and circulating...

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Bibliographic Details
Main Authors: Kunrong Yu, Wanying Li, Wenjie Long, Yijia Li, Yanting Li, Huili Liao, Jianhong Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Interstitial lung disease
Subtype
Protein
Mendelian randomization
Biomarker
Drug target
Online Access:https://doi.org/10.1038/s41598-025-85338-y
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