Optimizing chromosome dispersion quality: the key role of cell density

Optimizing chromosome dispersion quality: the key role of cell density

ObjectiveThis study aims to optimize metaphase dispersion in automated detection by quantitatively determining the optimal cell suspension density to enhance the accuracy and efficiency of chromosomal aberrations analysis.MethodsLymphocyte metaphase suspensions were prepared using an automated harve...

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Bibliographic Details
Main Authors:	Chao-Xian Gao, Li-Mei Li, Yu-Ting Chen, Ying-Yan Guo, Bo-Xin Li, Xue-Qin Yang, Chang-Ye Hui
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	automated detection cell density chromosome dispersion chromosomal aberrations radiation detection homogenization of detection
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1636498/full
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