Poly(4-vinylpyridinium)hydrogen sulfate: An efficient and recyclable Bronsted acid catalyst for the synthesis of fused 3,4-dihydropyrimidin-2(1H)-ones and thiones

Fused ring 3,4-dihydropyrimidin-2(1H)-ones and thiones were synthesized by the one-pot three component condensation of 6-methoxy-1-tetralone, aromatic aldehydes and urea or thiourea under solvent-free conditions at 120 °C utilizing poly(4-vinylpyridinium)hydrogen sulfate as Bronsted acid catalyst. T...

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Bibliographic Details
Main Authors: B. Janardhan, B. Rajitha, Peter A. Crooks
Format: Article
Language:English
Published: Springer 2016-09-01
Series:Journal of Saudi Chemical Society
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610312001585
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Summary:Fused ring 3,4-dihydropyrimidin-2(1H)-ones and thiones were synthesized by the one-pot three component condensation of 6-methoxy-1-tetralone, aromatic aldehydes and urea or thiourea under solvent-free conditions at 120 °C utilizing poly(4-vinylpyridinium)hydrogen sulfate as Bronsted acid catalyst. This methodology has an advantage of good yields, shorter reaction times, straight forward workup and reusability of the catalyst over five additional times without losing its activity and product yield.
ISSN:1319-6103