Subacute postoperative atrial fibrillation after heart surgery: Incidence and predictive factors in cardiac rehabilitation

Abstract Background Postoperative atrial fibrillation (POAF) is the most common arrhythmia following cardiac surgery (CS). It may occur between the 1st and the 4th postoperative day as acute POAF or between the 5th and the 30th as subacute (sPOAF). sPOAF is associated with higher thromboembolic risk...

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Main Authors: Vincenzo Rizza, Francesco Maranta, Lorenzo Cianfanelli, Iside Cartella, Francesco Maisano, Ottavio Alfieri, Domenico Cianflone
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Journal of Arrhythmia
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Online Access:https://doi.org/10.1002/joa3.12956
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author Vincenzo Rizza
Francesco Maranta
Lorenzo Cianfanelli
Iside Cartella
Francesco Maisano
Ottavio Alfieri
Domenico Cianflone
author_facet Vincenzo Rizza
Francesco Maranta
Lorenzo Cianfanelli
Iside Cartella
Francesco Maisano
Ottavio Alfieri
Domenico Cianflone
author_sort Vincenzo Rizza
collection DOAJ
description Abstract Background Postoperative atrial fibrillation (POAF) is the most common arrhythmia following cardiac surgery (CS). It may occur between the 1st and the 4th postoperative day as acute POAF or between the 5th and the 30th as subacute (sPOAF). sPOAF is associated with higher thromboembolic risk, which consistently increase patients' morbidity. Neutrophil‐to‐lymphocyte ratio (NLR) is a low‐cost inflammatory index proposed as possible POAF predictor. Identification of patients' risk categories might lead to improved postoperative outcomes. Methods The aim was to assess the incidence of sPOAF and to identify possible predictors in patients performing cardiovascular rehabilitation (CR) after CS. A single‐center cohort study was performed on 737 post‐surgical patients admitted to CR on sinus rhythm. Continuous monitoring with 12‐lead ECG telemetry was performed. We evaluated the predictive role of anamnestic, clinical, and laboratory data, including baseline NLR. Results Subacute POAF was documented in 170 cases (23.1%). At the multivariate analysis, age (OR 1.03; p = .001), mitral valve surgery (OR 1.77; p = .012), acute POAF (OR 2.97; p < .001), and NLR at baseline (OR 1.13; p = .042) were found to be independent predictive factors of sPOAF following heart surgery. Conclusions sPOAF is common after CS. Age, mitral valve procedures, acute POAF, and preoperative NLR were proved to increase sPOAF occurrence in CR. NLR is an affordable and reliable parameter which might be used to qualify the risk of arrhythmias at CR admission. Identification of new predictors of postoperative atrial fibrillation may allow to improve patients' prognosis.
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spelling doaj-art-bfa5f35cbcae405b9c70e35657913b812025-08-20T03:25:46ZengWileyJournal of Arrhythmia1880-42761883-21482024-02-01401677510.1002/joa3.12956Subacute postoperative atrial fibrillation after heart surgery: Incidence and predictive factors in cardiac rehabilitationVincenzo Rizza0Francesco Maranta1Lorenzo Cianfanelli2Iside Cartella3Francesco Maisano4Ottavio Alfieri5Domenico Cianflone6Vita‐Salute San Raffaele University Milan ItalyCardiac Rehabilitation Unit IRCCS San Raffaele Scientific Institute Milan ItalyCardiac Rehabilitation Unit IRCCS San Raffaele Scientific Institute Milan ItalySchool of Medicine and Surgery Milano‐Bicocca University Milan ItalyCardiac Surgery Unit IRCCS San Raffaele Scientific Institute Milan ItalyCardiac Surgery Unit IRCCS San Raffaele Scientific Institute Milan ItalyVita‐Salute San Raffaele University Milan ItalyAbstract Background Postoperative atrial fibrillation (POAF) is the most common arrhythmia following cardiac surgery (CS). It may occur between the 1st and the 4th postoperative day as acute POAF or between the 5th and the 30th as subacute (sPOAF). sPOAF is associated with higher thromboembolic risk, which consistently increase patients' morbidity. Neutrophil‐to‐lymphocyte ratio (NLR) is a low‐cost inflammatory index proposed as possible POAF predictor. Identification of patients' risk categories might lead to improved postoperative outcomes. Methods The aim was to assess the incidence of sPOAF and to identify possible predictors in patients performing cardiovascular rehabilitation (CR) after CS. A single‐center cohort study was performed on 737 post‐surgical patients admitted to CR on sinus rhythm. Continuous monitoring with 12‐lead ECG telemetry was performed. We evaluated the predictive role of anamnestic, clinical, and laboratory data, including baseline NLR. Results Subacute POAF was documented in 170 cases (23.1%). At the multivariate analysis, age (OR 1.03; p = .001), mitral valve surgery (OR 1.77; p = .012), acute POAF (OR 2.97; p < .001), and NLR at baseline (OR 1.13; p = .042) were found to be independent predictive factors of sPOAF following heart surgery. Conclusions sPOAF is common after CS. Age, mitral valve procedures, acute POAF, and preoperative NLR were proved to increase sPOAF occurrence in CR. NLR is an affordable and reliable parameter which might be used to qualify the risk of arrhythmias at CR admission. Identification of new predictors of postoperative atrial fibrillation may allow to improve patients' prognosis.https://doi.org/10.1002/joa3.12956atrial fibrillationcardiac rehabilitationcardiac surgeryneutrophil‐to‐lymphocyte ratiopostoperative complications
spellingShingle Vincenzo Rizza
Francesco Maranta
Lorenzo Cianfanelli
Iside Cartella
Francesco Maisano
Ottavio Alfieri
Domenico Cianflone
Subacute postoperative atrial fibrillation after heart surgery: Incidence and predictive factors in cardiac rehabilitation
Journal of Arrhythmia
atrial fibrillation
cardiac rehabilitation
cardiac surgery
neutrophil‐to‐lymphocyte ratio
postoperative complications
title Subacute postoperative atrial fibrillation after heart surgery: Incidence and predictive factors in cardiac rehabilitation
title_full Subacute postoperative atrial fibrillation after heart surgery: Incidence and predictive factors in cardiac rehabilitation
title_fullStr Subacute postoperative atrial fibrillation after heart surgery: Incidence and predictive factors in cardiac rehabilitation
title_full_unstemmed Subacute postoperative atrial fibrillation after heart surgery: Incidence and predictive factors in cardiac rehabilitation
title_short Subacute postoperative atrial fibrillation after heart surgery: Incidence and predictive factors in cardiac rehabilitation
title_sort subacute postoperative atrial fibrillation after heart surgery incidence and predictive factors in cardiac rehabilitation
topic atrial fibrillation
cardiac rehabilitation
cardiac surgery
neutrophil‐to‐lymphocyte ratio
postoperative complications
url https://doi.org/10.1002/joa3.12956
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