Legg-Calve´-Perthes disease - diagnostic value of acetabular-femoral head match index

Abstract Early treatment of Legg-Calve´-Perthes disease (LCPD)can improve hip joint activity and life management in adulthood. However, the current classification of LCPD is based on imaging findings in the fragmented stage of the disease, which is prone to delay treatment. Therefore the aim of this...

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Main Authors: Dun Zhao, Yinuo Fan, Wenru Guan, Hao Xiong, Bin Fang, Yue Li
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-79805-1
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author Dun Zhao
Yinuo Fan
Wenru Guan
Hao Xiong
Bin Fang
Yue Li
author_facet Dun Zhao
Yinuo Fan
Wenru Guan
Hao Xiong
Bin Fang
Yue Li
author_sort Dun Zhao
collection DOAJ
description Abstract Early treatment of Legg-Calve´-Perthes disease (LCPD)can improve hip joint activity and life management in adulthood. However, the current classification of LCPD is based on imaging findings in the fragmented stage of the disease, which is prone to delay treatment. Therefore the aim of this study is to evaluate the potential risk factors associated with poor radiological outcomes of LCPD, and to develop a new index for hip consistency evaluation, which can be used to speculate radiographic outcomes at the time of the first visit. The acetabular-femoral head match index (AFMI) of each enrolled subject was measured in standard anterior-posterior radiograph images. In the study of patients presenting during necrosis and fragmentation stage, a significant correlation was established between AFMI and modified Stulberg classification (P<0.05). The results of binary logistic regression analyses showed that Herring classification of fragmentation stage and AFMI were the main risk factors for flat hips. Thus, we provide evidence suggesting that AFMI has a potential role in predicting patients who do not respond well to conservative treatment. Although prospective multicenter studies are needed, these results provide useful clinical clues for the early treatment of LCPD.
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spelling doaj-art-bfa596b2e4e54a669a15d0edda0d74d72025-08-20T02:22:20ZengNature PortfolioScientific Reports2045-23222024-11-011411910.1038/s41598-024-79805-1Legg-Calve´-Perthes disease - diagnostic value of acetabular-femoral head match indexDun Zhao0Yinuo Fan1Wenru Guan2Hao Xiong3Bin Fang4Yue Li5Guangzhou University of Chinese MedicineGuangzhou University of Chinese MedicinePeople’s hospital of YangDong district YangJiang cityDepartment of Orthopedic, The First Affiliated Hospital of Guangzhou University of Chinese MedicineDepartment of Orthopedic, The First Affiliated Hospital of Guangzhou University of Chinese MedicineDepartment of Orthopedic, The First Affiliated Hospital of Guangzhou University of Chinese MedicineAbstract Early treatment of Legg-Calve´-Perthes disease (LCPD)can improve hip joint activity and life management in adulthood. However, the current classification of LCPD is based on imaging findings in the fragmented stage of the disease, which is prone to delay treatment. Therefore the aim of this study is to evaluate the potential risk factors associated with poor radiological outcomes of LCPD, and to develop a new index for hip consistency evaluation, which can be used to speculate radiographic outcomes at the time of the first visit. The acetabular-femoral head match index (AFMI) of each enrolled subject was measured in standard anterior-posterior radiograph images. In the study of patients presenting during necrosis and fragmentation stage, a significant correlation was established between AFMI and modified Stulberg classification (P<0.05). The results of binary logistic regression analyses showed that Herring classification of fragmentation stage and AFMI were the main risk factors for flat hips. Thus, we provide evidence suggesting that AFMI has a potential role in predicting patients who do not respond well to conservative treatment. Although prospective multicenter studies are needed, these results provide useful clinical clues for the early treatment of LCPD.https://doi.org/10.1038/s41598-024-79805-1Legg-Calve´-Perthes diseaseAcetabular-femoral head matchHerring classificationModified Stulberg classification
spellingShingle Dun Zhao
Yinuo Fan
Wenru Guan
Hao Xiong
Bin Fang
Yue Li
Legg-Calve´-Perthes disease - diagnostic value of acetabular-femoral head match index
Scientific Reports
Legg-Calve´-Perthes disease
Acetabular-femoral head match
Herring classification
Modified Stulberg classification
title Legg-Calve´-Perthes disease - diagnostic value of acetabular-femoral head match index
title_full Legg-Calve´-Perthes disease - diagnostic value of acetabular-femoral head match index
title_fullStr Legg-Calve´-Perthes disease - diagnostic value of acetabular-femoral head match index
title_full_unstemmed Legg-Calve´-Perthes disease - diagnostic value of acetabular-femoral head match index
title_short Legg-Calve´-Perthes disease - diagnostic value of acetabular-femoral head match index
title_sort legg calve´ perthes disease diagnostic value of acetabular femoral head match index
topic Legg-Calve´-Perthes disease
Acetabular-femoral head match
Herring classification
Modified Stulberg classification
url https://doi.org/10.1038/s41598-024-79805-1
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