From Invaginating Site to Deep Lesion: Spatial Transcriptomics Unravels Ectopic Endometrial Penetration Features in Adenomyosis

From Invaginating Site to Deep Lesion: Spatial Transcriptomics Unravels Ectopic Endometrial Penetration Features in Adenomyosis

Abstract Adenomyosis, characterized by clinical intractability, significantly impacts female fertility and life quality due to the absence of definitive diagnostic markers and effective treatment options. The invagination theory is a primary hypothesis for adenomyosis, but the underlying molecular m...

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Main Authors: Boyu Li, Jia Qi, Yumeng Cao, Yijing Long, Zhe Wei, Wang‐Sheng Wang, Shuanggang Hu, Yuan Wang, Qinling Zhu, Xiao Hu, Zhe Sun, Jie Zhu, Taiyang Ye, Yejie Yao, Yiwen Meng, Xuejiao Bian, Xinyi Dong, Hengyu Guan, Yunfei Huang, Yun Sun
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
adenomyosis
fibrosis
invagination
invasion
spatial transcriptomics
Online Access:https://doi.org/10.1002/advs.202411752
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https://doi.org/10.1002/advs.202411752

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