Deep generative AI models analyzing circulating orphan non-coding RNAs enable detection of early-stage lung cancer

Deep generative AI models analyzing circulating orphan non-coding RNAs enable detection of early-stage lung cancer

Abstract Liquid biopsies have the potential to revolutionize cancer care through non-invasive early detection of tumors. Developing a robust liquid biopsy test requires collecting high-dimensional data from a large number of blood samples across heterogeneous groups of patients. We propose that the...

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Main Authors: Mehran Karimzadeh, Amir Momen-Roknabadi, Taylor B. Cavazos, Yuqi Fang, Nae-Chyun Chen, Michael Multhaup, Jennifer Yen, Jeremy Ku, Jieyang Wang, Xuan Zhao, Philip Murzynowski, Kathleen Wang, Rose Hanna, Alice Huang, Diana Corti, Dang Nguyen, Ti Lam, Seda Kilinc, Patrick Arensdorf, Kimberly H. Chau, Anna Hartwig, Lisa Fish, Helen Li, Babak Behsaz, Olivier Elemento, James Zou, Fereydoun Hormozdiari, Babak Alipanahi, Hani Goodarzi
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53851-9
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