Surgical Treatment of Scoliosis in Patients with Osteogenesis Imperfecta

Patients with osteogenesis imperfecta (OI) face many challenges, including skeletal deformities and repeated extremity fractures. Spinal deformities in patients with OI are especially challenging for spine surgeons because of poor bone stock and rigid curves, often necessitating surgical treatment....

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Main Authors: Bienvenido Leo Antonio Caro, Anchelle Grace Ho, Samuel Arsenio Grozman, Anne Kathleen Ganal-Antonio
Format: Article
Language:English
Published: Philippine Orthopaedic Association, Inc. 2025-07-01
Series:Philippine Journal of Orthopaedics
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Online Access:https://philjorthopaedics.org/index.php/pjo/article/view/13477
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Summary:Patients with osteogenesis imperfecta (OI) face many challenges, including skeletal deformities and repeated extremity fractures. Spinal deformities in patients with OI are especially challenging for spine surgeons because of poor bone stock and rigid curves, often necessitating surgical treatment. This case report presents two OI patients with scoliosis managed in our institution. Patient A was a woman in her 20s, while patient B was in her 30s. Both had progression of curves past skeletal maturity and underwent pre-operative bisphosphonate therapy before deformity correction and instrumentation. Due to acceptable bone density preoperatively, non-fenestrated pedicle screws without cement augmentation were utilized for both patients. We did not encounter implant failure, junctional kyphosis, or pseudoarthrosis. Despite a loss of correction of 3% (midthoracic) and 9% (lumbar) for patient A and 2% (thoracic) and 6% (thoraco-lumbar) for patient B, both patients did not return to pre-operative measurements after 1 year of follow-up. They were also ambulatory and returned to employment postoperatively.
ISSN:0118-3362
2012-3264