Surgical treatment of unicentric plasma cell histological type Castleman's disease
Introduction. Castleman’s disease or angiofollicular lymph hyperplasia is a rare disease with two identified clinical forms. Unicentric or localized form is characterized by isolated growth of lymph nodes, most often in mediastinum, and multicentric form is expressed as systemic disease with spr...
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2011-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2011/0042-84501109795M.pdf |
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| author | Marić Nebojša Stanić Vojkan Cvijanović Vlado Ristanović Aleksandar Kovačević Snežana Krivokapić Žarko Tasić-Radić Olga |
| author_facet | Marić Nebojša Stanić Vojkan Cvijanović Vlado Ristanović Aleksandar Kovačević Snežana Krivokapić Žarko Tasić-Radić Olga |
| author_sort | Marić Nebojša |
| collection | DOAJ |
| description | Introduction. Castleman’s disease or angiofollicular lymph hyperplasia is a rare disease with two identified clinical forms. Unicentric or localized form is characterized by isolated growth of lymph nodes, most often in mediastinum, and multicentric form is expressed as systemic disease with spread lymphadenopathy, organomegaly and presence of general symptoms of the disease. Histological types are hyalovascular, plasma-cell and transitive (mixed) cell. Case report. This case report shows a woman, 59 years old, with unicentric form of plasma-cell type of Castleman’s disease. Unicentric form is usually shown as hyalovascular histological type, extremely rare as plasma-cell type, and transitive (mixed) cell type was never described in literature as localized clinical form. The disease was manifested with chest pain, loss of body weight, exhaustion and weakness of legs. Further diagnostic procedures found the presence of enlarged lymph nodes paratracheally right, in a close contact with vena cava superior. The disease was confirmed by histopathological analysis of bioptated mediastinal lymph node after mediastinoscopy. Surgical treatment included extirpation of enlarged lymph nodes. After the regular postoperative condition, a full therapy effect was confirmed. Conclusion. Unicentric form of Castleman’s disease is expressed with enlarged lymph nodes on predilected places, usually in mediastinum. Surgical treatment is best method for the management of the disease and brings a full recovery of patient. |
| format | Article |
| id | doaj-art-bfa1ba2ecd2b46be84e6f33882220062 |
| institution | DOAJ |
| issn | 0042-8450 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-bfa1ba2ecd2b46be84e6f338822200622025-08-20T03:22:39ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502011-01-0168979579910.2298/VSP1109795MSurgical treatment of unicentric plasma cell histological type Castleman's diseaseMarić NebojšaStanić VojkanCvijanović VladoRistanović AleksandarKovačević SnežanaKrivokapić ŽarkoTasić-Radić OlgaIntroduction. Castleman’s disease or angiofollicular lymph hyperplasia is a rare disease with two identified clinical forms. Unicentric or localized form is characterized by isolated growth of lymph nodes, most often in mediastinum, and multicentric form is expressed as systemic disease with spread lymphadenopathy, organomegaly and presence of general symptoms of the disease. Histological types are hyalovascular, plasma-cell and transitive (mixed) cell. Case report. This case report shows a woman, 59 years old, with unicentric form of plasma-cell type of Castleman’s disease. Unicentric form is usually shown as hyalovascular histological type, extremely rare as plasma-cell type, and transitive (mixed) cell type was never described in literature as localized clinical form. The disease was manifested with chest pain, loss of body weight, exhaustion and weakness of legs. Further diagnostic procedures found the presence of enlarged lymph nodes paratracheally right, in a close contact with vena cava superior. The disease was confirmed by histopathological analysis of bioptated mediastinal lymph node after mediastinoscopy. Surgical treatment included extirpation of enlarged lymph nodes. After the regular postoperative condition, a full therapy effect was confirmed. Conclusion. Unicentric form of Castleman’s disease is expressed with enlarged lymph nodes on predilected places, usually in mediastinum. Surgical treatment is best method for the management of the disease and brings a full recovery of patient.http://www.doiserbia.nb.rs/img/doi/0042-8450/2011/0042-84501109795M.pdfCastleman diseasethoracic surgical proceduresdiagnosistreatment outcome |
| spellingShingle | Marić Nebojša Stanić Vojkan Cvijanović Vlado Ristanović Aleksandar Kovačević Snežana Krivokapić Žarko Tasić-Radić Olga Surgical treatment of unicentric plasma cell histological type Castleman's disease Vojnosanitetski Pregled Castleman disease thoracic surgical procedures diagnosis treatment outcome |
| title | Surgical treatment of unicentric plasma cell histological type Castleman's disease |
| title_full | Surgical treatment of unicentric plasma cell histological type Castleman's disease |
| title_fullStr | Surgical treatment of unicentric plasma cell histological type Castleman's disease |
| title_full_unstemmed | Surgical treatment of unicentric plasma cell histological type Castleman's disease |
| title_short | Surgical treatment of unicentric plasma cell histological type Castleman's disease |
| title_sort | surgical treatment of unicentric plasma cell histological type castleman s disease |
| topic | Castleman disease thoracic surgical procedures diagnosis treatment outcome |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2011/0042-84501109795M.pdf |
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