Insights into the binding selectivity of harzianoic acids A and B to tetraspanin CD81

Aim: Harzianoic acids A and B (Hz-A/B) are two rare cyclobutene-containing sesquiterpenes isolated from a marine strain of the sponge-associated fungus Trichoderma harzianum. They display anticancer and antiviral effects, reducing the entry of hepatitis C virus (HCV) into hepatocarcinoma cells. The...

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Main Authors: Gérard Vergoten, Christian Bailly
Format: Article
Language:English
Published: Open Exploration 2023-11-01
Series:Exploration of Drug Science
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Online Access:https://www.explorationpub.com/uploads/Article/A100827/100827.pdf
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