Efficacy of intravenous human immunoglobulin in renal transplant recipients with moderate to severe pneumonia
Objective To investigate the intravenous human immunoglobulin therapy in renal transplant recipients with moderate to severe pulmonary infection.Methods From October 2005 to July 2015,48 patients with moderate to severe pulmonary infection after renal transplantation in our department were analyzed....
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Editorial Department of Journal of Clinical Nephrology
2017-01-01
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| Series: | Linchuang shenzangbing zazhi |
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| author | ZHU Bo-cheng GE Guo-jun REN Wen-li LOU Bo-yang ZHU Xiao-feng |
| author_facet | ZHU Bo-cheng GE Guo-jun REN Wen-li LOU Bo-yang ZHU Xiao-feng |
| author_sort | ZHU Bo-cheng |
| collection | DOAJ |
| description | Objective To investigate the intravenous human immunoglobulin therapy in renal transplant recipients with moderate to severe pulmonary infection.Methods From October 2005 to July 2015,48 patients with moderate to severe pulmonary infection after renal transplantation in our department were analyzed.Twenty patients given daily intravenous human immunoglobulin(20 g for 3to 7 days)were taken as the treatment group,and the rest 23 patients without given intravenous human immunoglobulin served as the control group.The basic immunosuppressant was given in both two groups.The infection control time,fatality rate,length of hospital stay,and the occurrence of acute rejection and other indicators were observed in both two groups.Results The infection control time in the treatment group was significantly shorter than in the control group[(11.78±3.30)d vs.(15.13±3.30)d,P=0.004)].Twenty-three cases survived and2 died in the treatment group,and16 cases survived and 7 died in the control group with the difference being statistically significant(P=0.047).There was no significant difference in the length of hospital stay between the treatment group and the control group[(32.78±13.93)d vs.(30±23.87)d].There was no acute rejection in the treatment group,and 2 cases of acute rejection in the control group.Conclusions Intravenous human immunoglobulin can significantly reduce fatality rate of the renal transplant recipients with moderate to severe pulmonary infection and can significantly shorten the time of infection control. |
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| institution | OA Journals |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2017-01-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
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| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-bf9604a6e35d499590a16f9bd7fe5fcc2025-08-20T02:28:49ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902017-01-0141541857917343Efficacy of intravenous human immunoglobulin in renal transplant recipients with moderate to severe pneumoniaZHU Bo-chengGE Guo-junREN Wen-liLOU Bo-yangZHU Xiao-fengObjective To investigate the intravenous human immunoglobulin therapy in renal transplant recipients with moderate to severe pulmonary infection.Methods From October 2005 to July 2015,48 patients with moderate to severe pulmonary infection after renal transplantation in our department were analyzed.Twenty patients given daily intravenous human immunoglobulin(20 g for 3to 7 days)were taken as the treatment group,and the rest 23 patients without given intravenous human immunoglobulin served as the control group.The basic immunosuppressant was given in both two groups.The infection control time,fatality rate,length of hospital stay,and the occurrence of acute rejection and other indicators were observed in both two groups.Results The infection control time in the treatment group was significantly shorter than in the control group[(11.78±3.30)d vs.(15.13±3.30)d,P=0.004)].Twenty-three cases survived and2 died in the treatment group,and16 cases survived and 7 died in the control group with the difference being statistically significant(P=0.047).There was no significant difference in the length of hospital stay between the treatment group and the control group[(32.78±13.93)d vs.(30±23.87)d].There was no acute rejection in the treatment group,and 2 cases of acute rejection in the control group.Conclusions Intravenous human immunoglobulin can significantly reduce fatality rate of the renal transplant recipients with moderate to severe pulmonary infection and can significantly shorten the time of infection control.http://www.lcszb.com/thesisDetails?columnId=57917343&Fpath=home&index=0Renal transplantationPulmonary infectionHuman immunoglobulin |
| spellingShingle | ZHU Bo-cheng GE Guo-jun REN Wen-li LOU Bo-yang ZHU Xiao-feng Efficacy of intravenous human immunoglobulin in renal transplant recipients with moderate to severe pneumonia Linchuang shenzangbing zazhi Renal transplantation Pulmonary infection Human immunoglobulin |
| title | Efficacy of intravenous human immunoglobulin in renal transplant recipients with moderate to severe pneumonia |
| title_full | Efficacy of intravenous human immunoglobulin in renal transplant recipients with moderate to severe pneumonia |
| title_fullStr | Efficacy of intravenous human immunoglobulin in renal transplant recipients with moderate to severe pneumonia |
| title_full_unstemmed | Efficacy of intravenous human immunoglobulin in renal transplant recipients with moderate to severe pneumonia |
| title_short | Efficacy of intravenous human immunoglobulin in renal transplant recipients with moderate to severe pneumonia |
| title_sort | efficacy of intravenous human immunoglobulin in renal transplant recipients with moderate to severe pneumonia |
| topic | Renal transplantation Pulmonary infection Human immunoglobulin |
| url | http://www.lcszb.com/thesisDetails?columnId=57917343&Fpath=home&index=0 |
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