Preparation and evaluation of Brucella T4SS recombinant proteins in serodiagnosis of human brucellosis based on TMT-based proteomics technology

Preparation and evaluation of Brucella T4SS recombinant proteins in serodiagnosis of human brucellosis based on TMT-based proteomics technology

IntroductionBrucellosis, a significant zoonotic infectious disease, poses a global health threat. Accurate and efficient diagnosis is crucial for prevention, control, and treatment of brucellosis. VirB proteins, components of the Type IV secretion system (T4SS) in Brucella, play a pivotal role in ba...

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Bibliographic Details
Main Authors: Qi Wu, Chen Sun, Liping Guo, Yujia Xie, Jinpeng Zhang, Dehui Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
brucellosis
type IV secretion system
VirB proteins
TMT proteomics
serodiagnosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1514046/full
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