Insights into quorum sensing (QS): QS-regulated biofilm and inhibitors
In the environment, bacteria can communicate with a known mechanism called quorum sensing (QS). These bacteria will communicate in a group for social interactions like a multi-cellular organism. It provides significant benefits to the bacteria in host colonization, the formation of biofilms, defens...
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| Format: | Article |
| Language: | English |
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HH Publisher
2020-11-01
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| Series: | Progress in Microbes and Molecular Biology |
| Online Access: | https://journals.hh-publisher.com/index.php/pmmb/article/view/350 |
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| _version_ | 1832541436149497856 |
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| author | Wen-Si Tan Jodi Woan-Fei Law Lydia Ngiik-Shiew Law Vengadesh Letchumanan Kok-Gan Chan |
| author_facet | Wen-Si Tan Jodi Woan-Fei Law Lydia Ngiik-Shiew Law Vengadesh Letchumanan Kok-Gan Chan |
| author_sort | Wen-Si Tan |
| collection | DOAJ |
| description |
In the environment, bacteria can communicate with a known mechanism called quorum sensing (QS). These bacteria will communicate in a group for social interactions like a multi-cellular organism. It provides significant benefits to the bacteria in host colonization, the formation of biofilms, defense against competitors, and adaptation to environmental changes. The bacteria that organize in biofilms are difficult to control and manage, resulting in a higher dosage of antibiotics to clear the infectious biofilms. Also, many QS-controlled activities are involved in virulence and pathogenicity. Hence, understanding the details of quorum sensing mechanisms, its phenotype regulation (biofilm), and QS inhibitors (which attenuate virulence/pathogenicity) may open a new avenue for controlling bacterial infections.
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| format | Article |
| id | doaj-art-bf8cd84c88a14592ae0ff5367220972a |
| institution | Kabale University |
| issn | 2637-1049 |
| language | English |
| publishDate | 2020-11-01 |
| publisher | HH Publisher |
| record_format | Article |
| series | Progress in Microbes and Molecular Biology |
| spelling | doaj-art-bf8cd84c88a14592ae0ff5367220972a2025-02-04T08:36:59ZengHH PublisherProgress in Microbes and Molecular Biology2637-10492020-11-013110.36877/pmmb.a0000141Insights into quorum sensing (QS): QS-regulated biofilm and inhibitorsWen-Si TanJodi Woan-Fei LawLydia Ngiik-Shiew LawVengadesh LetchumananKok-Gan Chan In the environment, bacteria can communicate with a known mechanism called quorum sensing (QS). These bacteria will communicate in a group for social interactions like a multi-cellular organism. It provides significant benefits to the bacteria in host colonization, the formation of biofilms, defense against competitors, and adaptation to environmental changes. The bacteria that organize in biofilms are difficult to control and manage, resulting in a higher dosage of antibiotics to clear the infectious biofilms. Also, many QS-controlled activities are involved in virulence and pathogenicity. Hence, understanding the details of quorum sensing mechanisms, its phenotype regulation (biofilm), and QS inhibitors (which attenuate virulence/pathogenicity) may open a new avenue for controlling bacterial infections. https://journals.hh-publisher.com/index.php/pmmb/article/view/350 |
| spellingShingle | Wen-Si Tan Jodi Woan-Fei Law Lydia Ngiik-Shiew Law Vengadesh Letchumanan Kok-Gan Chan Insights into quorum sensing (QS): QS-regulated biofilm and inhibitors Progress in Microbes and Molecular Biology |
| title | Insights into quorum sensing (QS): QS-regulated biofilm and inhibitors |
| title_full | Insights into quorum sensing (QS): QS-regulated biofilm and inhibitors |
| title_fullStr | Insights into quorum sensing (QS): QS-regulated biofilm and inhibitors |
| title_full_unstemmed | Insights into quorum sensing (QS): QS-regulated biofilm and inhibitors |
| title_short | Insights into quorum sensing (QS): QS-regulated biofilm and inhibitors |
| title_sort | insights into quorum sensing qs qs regulated biofilm and inhibitors |
| url | https://journals.hh-publisher.com/index.php/pmmb/article/view/350 |
| work_keys_str_mv | AT wensitan insightsintoquorumsensingqsqsregulatedbiofilmandinhibitors AT jodiwoanfeilaw insightsintoquorumsensingqsqsregulatedbiofilmandinhibitors AT lydiangiikshiewlaw insightsintoquorumsensingqsqsregulatedbiofilmandinhibitors AT vengadeshletchumanan insightsintoquorumsensingqsqsregulatedbiofilmandinhibitors AT kokganchan insightsintoquorumsensingqsqsregulatedbiofilmandinhibitors |