The Effectiveness of Conbercept Combined with Panretinal Photocoagulation vs. Panretinal Photocoagulation in the Treatment of Diabetic Retinopathy: A Meta-Analysis
Objective. This meta-analysis aimed to compare the effect and safety of conbercept with panretinal photocoagulation (PRP) vs. PRP in the treatment of diabetic retinopathy (DR). Methods. Relevant studies were identified through systemic searches of PubMed, EMBASE, China National Knowledge Infrastruct...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
|
| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2021/5591719 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850175499865686016 |
|---|---|
| author | Chao Huang Haiqing Ji Xuguang Han |
| author_facet | Chao Huang Haiqing Ji Xuguang Han |
| author_sort | Chao Huang |
| collection | DOAJ |
| description | Objective. This meta-analysis aimed to compare the effect and safety of conbercept with panretinal photocoagulation (PRP) vs. PRP in the treatment of diabetic retinopathy (DR). Methods. Relevant studies were identified through systemic searches of PubMed, EMBASE, China National Knowledge Infrastructure, and Wanfang database up to December 2020. The results of conbercept and PRP in patients with DR were analyzed, including overall effectiveness, best corrected visual acuity, central macular thickness, and complications. Results. 12 articles involving 1244 patients with DR were identified for this meta-analysis. The results of the meta-analysis showed that conbercept combined with PRP significantly increased the level of overall effectiveness and significantly reduced the central thickness of macula and the incidence of complications compared with the control group. Conclusions. Conbercept with PRP tended to be more effective than PRP alone in terms of functional outcomes for treating DR. |
| format | Article |
| id | doaj-art-bf89973fb0fb441da2cb1d844659b00c |
| institution | OA Journals |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-bf89973fb0fb441da2cb1d844659b00c2025-08-20T02:19:26ZengWileyJournal of Ophthalmology2090-004X2090-00582021-01-01202110.1155/2021/55917195591719The Effectiveness of Conbercept Combined with Panretinal Photocoagulation vs. Panretinal Photocoagulation in the Treatment of Diabetic Retinopathy: A Meta-AnalysisChao Huang0Haiqing Ji1Xuguang Han2Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan, Shandong, ChinaOutpatient Department, Weifang Eye Hospital, Weifang, Shandong, ChinaDepartment of Ophthalmology, Jinan Second People's Hospital, Jinan, Shandong, ChinaObjective. This meta-analysis aimed to compare the effect and safety of conbercept with panretinal photocoagulation (PRP) vs. PRP in the treatment of diabetic retinopathy (DR). Methods. Relevant studies were identified through systemic searches of PubMed, EMBASE, China National Knowledge Infrastructure, and Wanfang database up to December 2020. The results of conbercept and PRP in patients with DR were analyzed, including overall effectiveness, best corrected visual acuity, central macular thickness, and complications. Results. 12 articles involving 1244 patients with DR were identified for this meta-analysis. The results of the meta-analysis showed that conbercept combined with PRP significantly increased the level of overall effectiveness and significantly reduced the central thickness of macula and the incidence of complications compared with the control group. Conclusions. Conbercept with PRP tended to be more effective than PRP alone in terms of functional outcomes for treating DR.http://dx.doi.org/10.1155/2021/5591719 |
| spellingShingle | Chao Huang Haiqing Ji Xuguang Han The Effectiveness of Conbercept Combined with Panretinal Photocoagulation vs. Panretinal Photocoagulation in the Treatment of Diabetic Retinopathy: A Meta-Analysis Journal of Ophthalmology |
| title | The Effectiveness of Conbercept Combined with Panretinal Photocoagulation vs. Panretinal Photocoagulation in the Treatment of Diabetic Retinopathy: A Meta-Analysis |
| title_full | The Effectiveness of Conbercept Combined with Panretinal Photocoagulation vs. Panretinal Photocoagulation in the Treatment of Diabetic Retinopathy: A Meta-Analysis |
| title_fullStr | The Effectiveness of Conbercept Combined with Panretinal Photocoagulation vs. Panretinal Photocoagulation in the Treatment of Diabetic Retinopathy: A Meta-Analysis |
| title_full_unstemmed | The Effectiveness of Conbercept Combined with Panretinal Photocoagulation vs. Panretinal Photocoagulation in the Treatment of Diabetic Retinopathy: A Meta-Analysis |
| title_short | The Effectiveness of Conbercept Combined with Panretinal Photocoagulation vs. Panretinal Photocoagulation in the Treatment of Diabetic Retinopathy: A Meta-Analysis |
| title_sort | effectiveness of conbercept combined with panretinal photocoagulation vs panretinal photocoagulation in the treatment of diabetic retinopathy a meta analysis |
| url | http://dx.doi.org/10.1155/2021/5591719 |
| work_keys_str_mv | AT chaohuang theeffectivenessofconberceptcombinedwithpanretinalphotocoagulationvspanretinalphotocoagulationinthetreatmentofdiabeticretinopathyametaanalysis AT haiqingji theeffectivenessofconberceptcombinedwithpanretinalphotocoagulationvspanretinalphotocoagulationinthetreatmentofdiabeticretinopathyametaanalysis AT xuguanghan theeffectivenessofconberceptcombinedwithpanretinalphotocoagulationvspanretinalphotocoagulationinthetreatmentofdiabeticretinopathyametaanalysis AT chaohuang effectivenessofconberceptcombinedwithpanretinalphotocoagulationvspanretinalphotocoagulationinthetreatmentofdiabeticretinopathyametaanalysis AT haiqingji effectivenessofconberceptcombinedwithpanretinalphotocoagulationvspanretinalphotocoagulationinthetreatmentofdiabeticretinopathyametaanalysis AT xuguanghan effectivenessofconberceptcombinedwithpanretinalphotocoagulationvspanretinalphotocoagulationinthetreatmentofdiabeticretinopathyametaanalysis |