Prognosis analysis of sacrococcygeal teratoma—compared with patient size
IntroductionAdvancements in prenatal care have underscored the importance of understanding postnatal outcomes and prognosis in sacrococcygeal teratoma (SCT). However, giant SCTs continue to pose surgical challenges and are associated with increased morbidity and mortality. A clear, objective thresho...
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| Language: | English |
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Frontiers Media S.A.
2025-03-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2025.1513825/full |
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| author | Jueun Park Suhyeon Ha Hyunhee Kwon Seong Chul Kim Jung-Man Namgoong Dae Yeon Kim |
| author_facet | Jueun Park Suhyeon Ha Hyunhee Kwon Seong Chul Kim Jung-Man Namgoong Dae Yeon Kim |
| author_sort | Jueun Park |
| collection | DOAJ |
| description | IntroductionAdvancements in prenatal care have underscored the importance of understanding postnatal outcomes and prognosis in sacrococcygeal teratoma (SCT). However, giant SCTs continue to pose surgical challenges and are associated with increased morbidity and mortality. A clear, objective threshold for defining a “large” tumor relative to the patient's size remains undefined. This study aimed to establish objective tumor size indicators for predicting surgical outcomes and prognosis.MethodsData from 97 patients diagnosed with and surgically treated for SCT at Asan Medical Center from 2000 to 2021 was retrospectively reviewed. The tumor volume/birthweight ratio (VWR) and tumor length/height at birth ratio (LHR) were measured. Surgical outcomes and prognosis were evaluated based on these measures, including surgical complications, concomitant surgeries, long-term complications, and recurrence.ResultsAfter surgery, 38 patients experienced short-term complications, 18 required additional operations, 16 developed long-term complications, and 14 experienced tumor recurrence. Both VWR and LHR correlated with short and long-term complications, additional surgeries, and recurrence.DiscussionThe small patient population limited the determination of precise cut-off values; however, a significant difference was observed between groups stratified by the most predictive cut-off values. Both objective tumor size indicators were significantly associated with prognosis and surgical outcomes. Notably, both indicators exhibited comparable predictive capabilities without discrepancies. |
| format | Article |
| id | doaj-art-bf8594ddbc4d416e9190b6ce6c7e53d4 |
| institution | Kabale University |
| issn | 2296-2360 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj-art-bf8594ddbc4d416e9190b6ce6c7e53d42025-08-20T03:40:03ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602025-03-011310.3389/fped.2025.15138251513825Prognosis analysis of sacrococcygeal teratoma—compared with patient sizeJueun ParkSuhyeon HaHyunhee KwonSeong Chul KimJung-Man NamgoongDae Yeon KimIntroductionAdvancements in prenatal care have underscored the importance of understanding postnatal outcomes and prognosis in sacrococcygeal teratoma (SCT). However, giant SCTs continue to pose surgical challenges and are associated with increased morbidity and mortality. A clear, objective threshold for defining a “large” tumor relative to the patient's size remains undefined. This study aimed to establish objective tumor size indicators for predicting surgical outcomes and prognosis.MethodsData from 97 patients diagnosed with and surgically treated for SCT at Asan Medical Center from 2000 to 2021 was retrospectively reviewed. The tumor volume/birthweight ratio (VWR) and tumor length/height at birth ratio (LHR) were measured. Surgical outcomes and prognosis were evaluated based on these measures, including surgical complications, concomitant surgeries, long-term complications, and recurrence.ResultsAfter surgery, 38 patients experienced short-term complications, 18 required additional operations, 16 developed long-term complications, and 14 experienced tumor recurrence. Both VWR and LHR correlated with short and long-term complications, additional surgeries, and recurrence.DiscussionThe small patient population limited the determination of precise cut-off values; however, a significant difference was observed between groups stratified by the most predictive cut-off values. Both objective tumor size indicators were significantly associated with prognosis and surgical outcomes. Notably, both indicators exhibited comparable predictive capabilities without discrepancies.https://www.frontiersin.org/articles/10.3389/fped.2025.1513825/fullsacrococcygeal teratomaprognosissurgical complicationpediatric surgerypediatric oncology |
| spellingShingle | Jueun Park Suhyeon Ha Hyunhee Kwon Seong Chul Kim Jung-Man Namgoong Dae Yeon Kim Prognosis analysis of sacrococcygeal teratoma—compared with patient size Frontiers in Pediatrics sacrococcygeal teratoma prognosis surgical complication pediatric surgery pediatric oncology |
| title | Prognosis analysis of sacrococcygeal teratoma—compared with patient size |
| title_full | Prognosis analysis of sacrococcygeal teratoma—compared with patient size |
| title_fullStr | Prognosis analysis of sacrococcygeal teratoma—compared with patient size |
| title_full_unstemmed | Prognosis analysis of sacrococcygeal teratoma—compared with patient size |
| title_short | Prognosis analysis of sacrococcygeal teratoma—compared with patient size |
| title_sort | prognosis analysis of sacrococcygeal teratoma compared with patient size |
| topic | sacrococcygeal teratoma prognosis surgical complication pediatric surgery pediatric oncology |
| url | https://www.frontiersin.org/articles/10.3389/fped.2025.1513825/full |
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