Carotid artery doppler study in patients of myocardial infarction and its correlation with other atherosclerotic risk factors: A cross-sectional study
Background: Carotid Doppler (CD) findings, including stenosis, increased carotid intima-media thickness (CIMT) and plaques, are linked to a higher risk of myocardial infarction (MI). Atherosclerotic risk factors play a key role in these changes. However, limited research has examined the association...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
KIMS Foundation and Research Center
2025-03-01
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| Series: | Journal of Medical and Scientific Research |
| Subjects: | |
| Online Access: | https://jmsronline.com/archive-article/Carotid-artery-doppler-myocardial-infarction-atherosclerotic |
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| Summary: | Background: Carotid Doppler (CD) findings, including stenosis, increased carotid intima-media thickness (CIMT) and plaques, are linked to a higher risk of myocardial infarction (MI). Atherosclerotic risk factors play a key role in these changes. However, limited research has examined the association of these CD characteristics with risk factors in Indian patients with MI. This study evaluated the association of atherosclerotic risk factors with CD findings and the association between CIMT and coronary angiography (CAG) findings in MI patients.
Materials and methods: This cross-sectional study was conducted over 24 months from February 2022 to January 2023 in the Cardiology department of a tertiary care hospital. A total of 50 patients with acute MI were included, and sociodemographic data, atherosclerotic risk factors, and biochemical parameters were recorded. All the patients underwent both CD and CAG.
Results: CD findings had a negative and significant correlation with high-density lipoprotein (HDL) (r=-0.51, p<0.001). The CD findings had positive, and significant correlations with systolic blood pressure (r=0.34, p=0.017), total cholesterol (r=0.34, p=0.015), waist circumference (r=0.36, p=0.011), serum triglycerides (r=0.37, p=0.009), and low-density lipoprotein (LDL) (r=0.38, p=0.007). The LDL/HDL ratio (r=0.41, p=0.003) and HbA1c (r=0.72, p<0.001) showed positive, and significant correlations with CD findings. CIMT >1 mm was significantly associated with triglycerides >200 mg/dL, HDL <40 mg/dL, obesity, and HbA1c ≥ 6.5% (p<0.05). Dyslipidemia and diabetes were significantly associated with the plaques (p<0.05). Mean CIMT was significantly associated with CAG findings (p<0.001).
Conclusion: CD findings, particularly CIMT and plaques, are significantly associated with dyslipidemia, diabetes, and CAD severity. |
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| ISSN: | 2321-1326 2394-112X |