Survival analysis of COVID-19 versus non-COVID-19 patients requiring intensive care for acute respiratory distress syndrome: An observational retrospective study
# Background/Aim This study analyzed clinical factors impacting the survival of COVID-19 patients with acute respiratory distress síndrome, or ARDS (CARDS) to ICU compared to non-COVID-19 ARDS patients. # Methods Clinical variables from 1,008 CARDS cases and 332 ARDS cases were computed using lea...
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| Format: | Article |
| Language: | English |
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Canadian Society of Respiratory Therapists
2024-08-01
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| Series: | Canadian Journal of Respiratory Therapy |
| Online Access: | https://doi.org/10.29390/001c.122402 |
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| _version_ | 1825139348491730944 |
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| author | Paulo Navas Boada Kevin Chamorro Santiago Ballaz |
| author_facet | Paulo Navas Boada Kevin Chamorro Santiago Ballaz |
| author_sort | Paulo Navas Boada |
| collection | DOAJ |
| description | # Background/Aim
This study analyzed clinical factors impacting the survival of COVID-19 patients with acute respiratory distress síndrome, or ARDS (CARDS) to ICU compared to non-COVID-19 ARDS patients.
# Methods
Clinical variables from 1,008 CARDS cases and 332 ARDS cases were computed using learning algorithms. The multivariable Cox proportional hazards regression models with the enter method evaluated risk factors and ICU mortality relationships. The survival analysis was completed with Kaplan-Meier and the log-rank tests.
# Results
A Random Forest model revealed that mechanical ventilation-related factors, oxygenation, blood pH, superinfection, shock, and ICU length of stay have the greatest effects on ICU survival. According to a multivariate Cox model, reintubation and a high-flow nasal cannula were essential for survival in CARDS patients during the ICU stay. The length of stay in the ICU diminishes in patients older than 45 years, regardless of the source of ARDS.
# Conclusion
This study gives recommendations for the respiratory care of ARDS in COVID-19 patients. |
| format | Article |
| id | doaj-art-bf746bd2f0984257a915160773db9e27 |
| institution | Kabale University |
| issn | 2368-6820 |
| language | English |
| publishDate | 2024-08-01 |
| publisher | Canadian Society of Respiratory Therapists |
| record_format | Article |
| series | Canadian Journal of Respiratory Therapy |
| spelling | doaj-art-bf746bd2f0984257a915160773db9e272025-02-11T20:30:52ZengCanadian Society of Respiratory TherapistsCanadian Journal of Respiratory Therapy2368-68202024-08-0160Survival analysis of COVID-19 versus non-COVID-19 patients requiring intensive care for acute respiratory distress syndrome: An observational retrospective studyPaulo Navas BoadaKevin ChamorroSantiago Ballaz# Background/Aim This study analyzed clinical factors impacting the survival of COVID-19 patients with acute respiratory distress síndrome, or ARDS (CARDS) to ICU compared to non-COVID-19 ARDS patients. # Methods Clinical variables from 1,008 CARDS cases and 332 ARDS cases were computed using learning algorithms. The multivariable Cox proportional hazards regression models with the enter method evaluated risk factors and ICU mortality relationships. The survival analysis was completed with Kaplan-Meier and the log-rank tests. # Results A Random Forest model revealed that mechanical ventilation-related factors, oxygenation, blood pH, superinfection, shock, and ICU length of stay have the greatest effects on ICU survival. According to a multivariate Cox model, reintubation and a high-flow nasal cannula were essential for survival in CARDS patients during the ICU stay. The length of stay in the ICU diminishes in patients older than 45 years, regardless of the source of ARDS. # Conclusion This study gives recommendations for the respiratory care of ARDS in COVID-19 patients.https://doi.org/10.29390/001c.122402 |
| spellingShingle | Paulo Navas Boada Kevin Chamorro Santiago Ballaz Survival analysis of COVID-19 versus non-COVID-19 patients requiring intensive care for acute respiratory distress syndrome: An observational retrospective study Canadian Journal of Respiratory Therapy |
| title | Survival analysis of COVID-19 versus non-COVID-19 patients requiring intensive care for acute respiratory distress syndrome: An observational retrospective study |
| title_full | Survival analysis of COVID-19 versus non-COVID-19 patients requiring intensive care for acute respiratory distress syndrome: An observational retrospective study |
| title_fullStr | Survival analysis of COVID-19 versus non-COVID-19 patients requiring intensive care for acute respiratory distress syndrome: An observational retrospective study |
| title_full_unstemmed | Survival analysis of COVID-19 versus non-COVID-19 patients requiring intensive care for acute respiratory distress syndrome: An observational retrospective study |
| title_short | Survival analysis of COVID-19 versus non-COVID-19 patients requiring intensive care for acute respiratory distress syndrome: An observational retrospective study |
| title_sort | survival analysis of covid 19 versus non covid 19 patients requiring intensive care for acute respiratory distress syndrome an observational retrospective study |
| url | https://doi.org/10.29390/001c.122402 |
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