Anxiety and depression in inflammatory eye disease: exploring the potential impact of topical treatment frequency as a putative psychometric item
Objective To evaluate whether topical therapy is linked to scores related to anxiety, depression and quality of life (QoL) in inflammatory eye disease (IED).Methods and analysis Patients with ocular surface disease (OSD, N=100) and Uveitis (N=100) completed self-administered validated questions on o...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2021-09-01
|
| Series: | BMJ Open Ophthalmology |
| Online Access: | https://bmjophth.bmj.com/content/6/1/e000649.full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850203408591486976 |
|---|---|
| author | Philip I Murray James Hodson Saaeha Rauz Paolo Scollo Georgios Vakros |
| author_facet | Philip I Murray James Hodson Saaeha Rauz Paolo Scollo Georgios Vakros |
| author_sort | Philip I Murray |
| collection | DOAJ |
| description | Objective To evaluate whether topical therapy is linked to scores related to anxiety, depression and quality of life (QoL) in inflammatory eye disease (IED).Methods and analysis Patients with ocular surface disease (OSD, N=100) and Uveitis (N=100) completed self-administered validated questions on ocular symptoms and well-being, with supplemental questions on eye drop frequency.Results Forty (20%) patients had scores consistent with depression and 33 (17%) anxiety. Anxiety, depression, QoL and OSD index (OSDI) scores did not differ significantly between OSD and Uveitis groups. In those with anxiety or depression, QoL was significantly reduced in all WHO Quality Of Life-BREF domains (all p<0.001). Multivariable analysis considering demographic and disease-related factors found daily topical drop frequency to be independently associated with anxiety (p=0.009) but not depression (p=0.300).Conclusion A high proportion of patients with IED demonstrated scores indicative of anxiety and depression. Preliminary evidence suggests that the frequency of topical eye drops potentially plays a significant role in the psychological health status of patients with IED . |
| format | Article |
| id | doaj-art-bf58b0ca1e43453e859d386ecff36d41 |
| institution | OA Journals |
| issn | 2397-3269 |
| language | English |
| publishDate | 2021-09-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open Ophthalmology |
| spelling | doaj-art-bf58b0ca1e43453e859d386ecff36d412025-08-20T02:11:31ZengBMJ Publishing GroupBMJ Open Ophthalmology2397-32692021-09-016110.1136/bmjophth-2020-000649Anxiety and depression in inflammatory eye disease: exploring the potential impact of topical treatment frequency as a putative psychometric itemPhilip I Murray0James Hodson1Saaeha Rauz2Paolo Scollo3Georgios Vakros42Birmingham and Midland Eye Centre, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham UKResearch Development and Innovation, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UKOphthalmology, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UKUO Ostetricia e Ginecologia, Dipartimento Materno-Infantile, Ospedale Cannizzaro, Catania, ItalyAcademic Unit of Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UKObjective To evaluate whether topical therapy is linked to scores related to anxiety, depression and quality of life (QoL) in inflammatory eye disease (IED).Methods and analysis Patients with ocular surface disease (OSD, N=100) and Uveitis (N=100) completed self-administered validated questions on ocular symptoms and well-being, with supplemental questions on eye drop frequency.Results Forty (20%) patients had scores consistent with depression and 33 (17%) anxiety. Anxiety, depression, QoL and OSD index (OSDI) scores did not differ significantly between OSD and Uveitis groups. In those with anxiety or depression, QoL was significantly reduced in all WHO Quality Of Life-BREF domains (all p<0.001). Multivariable analysis considering demographic and disease-related factors found daily topical drop frequency to be independently associated with anxiety (p=0.009) but not depression (p=0.300).Conclusion A high proportion of patients with IED demonstrated scores indicative of anxiety and depression. Preliminary evidence suggests that the frequency of topical eye drops potentially plays a significant role in the psychological health status of patients with IED .https://bmjophth.bmj.com/content/6/1/e000649.full |
| spellingShingle | Philip I Murray James Hodson Saaeha Rauz Paolo Scollo Georgios Vakros Anxiety and depression in inflammatory eye disease: exploring the potential impact of topical treatment frequency as a putative psychometric item BMJ Open Ophthalmology |
| title | Anxiety and depression in inflammatory eye disease: exploring the potential impact of topical treatment frequency as a putative psychometric item |
| title_full | Anxiety and depression in inflammatory eye disease: exploring the potential impact of topical treatment frequency as a putative psychometric item |
| title_fullStr | Anxiety and depression in inflammatory eye disease: exploring the potential impact of topical treatment frequency as a putative psychometric item |
| title_full_unstemmed | Anxiety and depression in inflammatory eye disease: exploring the potential impact of topical treatment frequency as a putative psychometric item |
| title_short | Anxiety and depression in inflammatory eye disease: exploring the potential impact of topical treatment frequency as a putative psychometric item |
| title_sort | anxiety and depression in inflammatory eye disease exploring the potential impact of topical treatment frequency as a putative psychometric item |
| url | https://bmjophth.bmj.com/content/6/1/e000649.full |
| work_keys_str_mv | AT philipimurray anxietyanddepressionininflammatoryeyediseaseexploringthepotentialimpactoftopicaltreatmentfrequencyasaputativepsychometricitem AT jameshodson anxietyanddepressionininflammatoryeyediseaseexploringthepotentialimpactoftopicaltreatmentfrequencyasaputativepsychometricitem AT saaeharauz anxietyanddepressionininflammatoryeyediseaseexploringthepotentialimpactoftopicaltreatmentfrequencyasaputativepsychometricitem AT paoloscollo anxietyanddepressionininflammatoryeyediseaseexploringthepotentialimpactoftopicaltreatmentfrequencyasaputativepsychometricitem AT georgiosvakros anxietyanddepressionininflammatoryeyediseaseexploringthepotentialimpactoftopicaltreatmentfrequencyasaputativepsychometricitem |