Differential Replication and Oncolytic Effects of Zika Virus in Aggressive CNS Tumor Cells: Insights from Organoid and Tumoroid Models

Differential Replication and Oncolytic Effects of Zika Virus in Aggressive CNS Tumor Cells: Insights from Organoid and Tumoroid Models

Central nervous system (CNS) cancers are responsible for high rates of morbidity and mortality worldwide. Malignant CNS tumors such as adult Glioblastoma (GBM) and pediatric embryonal CNS tumors such as medulloblastoma (MED) and atypical teratoid rhabdoid tumors (ATRT) present relevant therapeutic c...

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Bibliographic Details
Main Authors: Rodolfo Sanches Ferreira, Elisa Helena Farias Jandrey, Isabela Granha, Alice Kei Endo, Raiane Oliveira Ferreira, Bruno Henrique Silva Araujo, Mayana Zatz, Oswaldo Keith Okamoto
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Viruses
Subjects:
cancer
Zika virus
brain organoids
central nervous system tumors
glioblastoma
medulloblastoma
Online Access:https://www.mdpi.com/1999-4915/16/11/1764
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