Neurodevelopment at 10 months and 2–3 years old after early and prolonged anaesthesia in infancy: General Anaesthesia & Brain Activity study (GABA) secondary analysis

Neurodevelopment at 10 months and 2–3 years old after early and prolonged anaesthesia in infancy: General Anaesthesia & Brain Activity study (GABA) secondary analysis

Background: Effects of early and prolonged exposure to general anaesthesia on the developing brain are unclear. The study objective was to examine developmental outcomes at 10 months and 2–3 yr of age after general anaesthesia planned for >2 h in the first 2 months of life. Methods: This is a sec...

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Bibliographic Details
Main Authors: Laura Cornelissen, Siobhan Coffman, Isabelle Kim, Ellen Underwood, Alice Tao, Maria G. Maloney, Carolina Donado, Kimberly Lobo, Charles A. Nelson, Takao K. Hensch, Laurel J. Gabard-Durnam, Charles B. Berde
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:BJA Open
Subjects:
anaesthesia
cognition
critical period
early intervention
infant outcomes
neurodevelopment
Online Access:http://www.sciencedirect.com/science/article/pii/S2772609625000073
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