A Case of Combined Hepatocellular‐Cholangiocarcinoma Diagnosis and Treatment With Literature Review

ABSTRACT This report presents a rare case of a 43‐year‐old man with unresectable combined hepatocellular‐cholangiocarcinoma who, after undergoing transarterial chemoembolization, systemic chemotherapy, and stereotactic body radiation therapy, accepted curative resection and obtained an overall survi...

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Main Authors: Xuliang Chen, Hengkai Zhu, Liyan Tao, Shusen Zheng, Hua Guo
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.70652
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author Xuliang Chen
Hengkai Zhu
Liyan Tao
Shusen Zheng
Hua Guo
author_facet Xuliang Chen
Hengkai Zhu
Liyan Tao
Shusen Zheng
Hua Guo
author_sort Xuliang Chen
collection DOAJ
description ABSTRACT This report presents a rare case of a 43‐year‐old man with unresectable combined hepatocellular‐cholangiocarcinoma who, after undergoing transarterial chemoembolization, systemic chemotherapy, and stereotactic body radiation therapy, accepted curative resection and obtained an overall survival of 25 months to date. The case highlights the need for adaptable treatment regimens due to the tumor's components and underscores the importance of surgery for long‐term success.
format Article
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institution Kabale University
issn 2050-0904
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publisher Wiley
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series Clinical Case Reports
spelling doaj-art-bf46da48422a47afbed8c780e0f12cb02025-08-22T07:33:07ZengWileyClinical Case Reports2050-09042025-08-01138n/an/a10.1002/ccr3.70652A Case of Combined Hepatocellular‐Cholangiocarcinoma Diagnosis and Treatment With Literature ReviewXuliang Chen0Hengkai Zhu1Liyan Tao2Shusen Zheng3Hua Guo4Department of Hepatobiliary and Pancreatic Surgery, Key Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Shulan (Hangzhou) Hospital, Shulan International Medical College Zhejiang Shuren University Hangzhou P. R. ChinaDepartment of Hepatobiliary and Pancreatic Surgery, Key Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Shulan (Hangzhou) Hospital, Shulan International Medical College Zhejiang Shuren University Hangzhou P. R. ChinaDepartment of Hepatobiliary and Pancreatic Surgery, Key Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Shulan (Hangzhou) Hospital, Shulan International Medical College Zhejiang Shuren University Hangzhou P. R. ChinaDepartment of Hepatobiliary and Pancreatic Surgery, Key Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Shulan (Hangzhou) Hospital, Shulan International Medical College Zhejiang Shuren University Hangzhou P. R. ChinaDepartment of Hepatobiliary and Pancreatic Surgery, Key Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Shulan (Hangzhou) Hospital, Shulan International Medical College Zhejiang Shuren University Hangzhou P. R. ChinaABSTRACT This report presents a rare case of a 43‐year‐old man with unresectable combined hepatocellular‐cholangiocarcinoma who, after undergoing transarterial chemoembolization, systemic chemotherapy, and stereotactic body radiation therapy, accepted curative resection and obtained an overall survival of 25 months to date. The case highlights the need for adaptable treatment regimens due to the tumor's components and underscores the importance of surgery for long‐term success.https://doi.org/10.1002/ccr3.70652adult liver cancercancer reportschemoembolizationdrug therapyhepatectomyradiotherapy
spellingShingle Xuliang Chen
Hengkai Zhu
Liyan Tao
Shusen Zheng
Hua Guo
A Case of Combined Hepatocellular‐Cholangiocarcinoma Diagnosis and Treatment With Literature Review
Clinical Case Reports
adult liver cancer
cancer reports
chemoembolization
drug therapy
hepatectomy
radiotherapy
title A Case of Combined Hepatocellular‐Cholangiocarcinoma Diagnosis and Treatment With Literature Review
title_full A Case of Combined Hepatocellular‐Cholangiocarcinoma Diagnosis and Treatment With Literature Review
title_fullStr A Case of Combined Hepatocellular‐Cholangiocarcinoma Diagnosis and Treatment With Literature Review
title_full_unstemmed A Case of Combined Hepatocellular‐Cholangiocarcinoma Diagnosis and Treatment With Literature Review
title_short A Case of Combined Hepatocellular‐Cholangiocarcinoma Diagnosis and Treatment With Literature Review
title_sort case of combined hepatocellular cholangiocarcinoma diagnosis and treatment with literature review
topic adult liver cancer
cancer reports
chemoembolization
drug therapy
hepatectomy
radiotherapy
url https://doi.org/10.1002/ccr3.70652
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