Nerve Sheath Myxoma Masquerading as a Parotid Tumor-A Clinical Case Report
This case report discusses a rare instance of Nerve Sheath Myxoma (NSM), a benign tumour originating from peripheral nerve Schwann cells. While typically found in the distal extremities, this case involved a 10-year-old girl with a mass in the parotid region, presenting a unique challenge in diagnos...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Istanbul University Press
2025-03-01
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| Series: | The Turkish Journal of Ear Nose and Throat |
| Subjects: | |
| Online Access: | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/00029E8D453B4FE7B40094FDD0C6B428 |
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| Summary: | This case report discusses a rare instance of Nerve Sheath Myxoma (NSM), a benign tumour originating from peripheral nerve Schwann cells. While typically found in the distal extremities, this case involved a 10-year-old girl with a mass in the parotid region, presenting a unique challenge in diagnosis. Initial clinical assessments suggested a benign salivary gland tumour, but inconclusive FNAC results and conflicting CE-MRI findings led to the excision of the lesion. Histopathological examination revealed a well-circumscribed, multinodular hypocellular myxoid tumour consistent with NSM. Immunohistochem istry confirmed the diagnosis, showing positivity for S100, EMA, Vimentin, and CD34. This study highlights the importance of immunohistochemistry in differentiating NSM from other entities, particularly neu rothekeoma. The treatment of choice is wide local excision with tumour-free margins, and while local recurrences are reported, malignant transformation is undocumented. In conclusion, clinical and imaging techniques may struggle to accurately identify NSM, necessitating reliance on histopathology and immunohistochemistry for diagnosis. |
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| ISSN: | 2602-4837 |