Allelic selection of amplicons in glioblastoma revealed by combining somatic and germline analysis.

Cancer is a disease driven by a combination of inherited risk alleles coupled with the acquisition of somatic mutations, including amplification and deletion of genomic DNA. Potential relationships between the inherited and somatic aspects of the disease have only rarely been examined on a genome-wi...

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Bibliographic Details
Main Authors: Thomas LaFramboise, Ninad Dewal, Katherine Wilkins, Itsik Pe'er, Matthew L Freedman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1001086&type=printable
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