Evaluating the Efficacy of Chemical and Herbal Endodontic Irrigants in Smear Layer Removal: An In-vitro Analysis

Aim: The current research is designed to analyze the smear layer (SL) removal efficacy of different endodontic irrigants via scanning electron microscope (SEM). Materials and Methods: Eighty extracted premolars were gathered and allocated into four groups (n = 20) based on the array of endodontic ir...

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Main Authors: Kanika Singh Dhull, Nayana Shriram Anasane, Sumit Singh, D. R. Mahesh, Vinay Rao, Meena Jain
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-05-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_371_25
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author Kanika Singh Dhull
Nayana Shriram Anasane
Sumit Singh
D. R. Mahesh
Vinay Rao
Meena Jain
author_facet Kanika Singh Dhull
Nayana Shriram Anasane
Sumit Singh
D. R. Mahesh
Vinay Rao
Meena Jain
author_sort Kanika Singh Dhull
collection DOAJ
description Aim: The current research is designed to analyze the smear layer (SL) removal efficacy of different endodontic irrigants via scanning electron microscope (SEM). Materials and Methods: Eighty extracted premolars were gathered and allocated into four groups (n = 20) based on the array of endodontic irrigants employed: Group 1: Normal saline (NS), Group 2: 17% EDTA (Ethylenediaminetetraacetic acid), Group 3: Neem leaf extract (NLE), and Group 4: Garlic solution (GS). SL elimination was evaluated beneath SEM at upper, intermediate, and apical levels of root canals. Results: The acquired data was evaluated using the non-parametric equivalent test. Groups 2 and 3 had the most effective SL clearance performance, followed by Group 4, while Group 1 had the lowest effectiveness at the upper, intermediate, and apical levels. An intergroup comparison revealed that Group 3 had successful SL reduction at the apical level. Conclusion: Group 3 outperformed the other groups in eliminating the SL at the upper, intermediate, and apical thirds.
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issn 0976-4879
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publishDate 2025-05-01
publisher Wolters Kluwer Medknow Publications
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spelling doaj-art-bf19aa791d7844e3a5c3a20b397c69a02025-08-20T02:03:24ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062025-05-0117Suppl 1S774S77610.4103/jpbs.jpbs_371_25Evaluating the Efficacy of Chemical and Herbal Endodontic Irrigants in Smear Layer Removal: An In-vitro AnalysisKanika Singh DhullNayana Shriram AnasaneSumit SinghD. R. MaheshVinay RaoMeena JainAim: The current research is designed to analyze the smear layer (SL) removal efficacy of different endodontic irrigants via scanning electron microscope (SEM). Materials and Methods: Eighty extracted premolars were gathered and allocated into four groups (n = 20) based on the array of endodontic irrigants employed: Group 1: Normal saline (NS), Group 2: 17% EDTA (Ethylenediaminetetraacetic acid), Group 3: Neem leaf extract (NLE), and Group 4: Garlic solution (GS). SL elimination was evaluated beneath SEM at upper, intermediate, and apical levels of root canals. Results: The acquired data was evaluated using the non-parametric equivalent test. Groups 2 and 3 had the most effective SL clearance performance, followed by Group 4, while Group 1 had the lowest effectiveness at the upper, intermediate, and apical levels. An intergroup comparison revealed that Group 3 had successful SL reduction at the apical level. Conclusion: Group 3 outperformed the other groups in eliminating the SL at the upper, intermediate, and apical thirds.https://journals.lww.com/10.4103/jpbs.jpbs_371_25chemical irrigationherbal irrigationsemsmear layer
spellingShingle Kanika Singh Dhull
Nayana Shriram Anasane
Sumit Singh
D. R. Mahesh
Vinay Rao
Meena Jain
Evaluating the Efficacy of Chemical and Herbal Endodontic Irrigants in Smear Layer Removal: An In-vitro Analysis
Journal of Pharmacy and Bioallied Sciences
chemical irrigation
herbal irrigation
sem
smear layer
title Evaluating the Efficacy of Chemical and Herbal Endodontic Irrigants in Smear Layer Removal: An In-vitro Analysis
title_full Evaluating the Efficacy of Chemical and Herbal Endodontic Irrigants in Smear Layer Removal: An In-vitro Analysis
title_fullStr Evaluating the Efficacy of Chemical and Herbal Endodontic Irrigants in Smear Layer Removal: An In-vitro Analysis
title_full_unstemmed Evaluating the Efficacy of Chemical and Herbal Endodontic Irrigants in Smear Layer Removal: An In-vitro Analysis
title_short Evaluating the Efficacy of Chemical and Herbal Endodontic Irrigants in Smear Layer Removal: An In-vitro Analysis
title_sort evaluating the efficacy of chemical and herbal endodontic irrigants in smear layer removal an in vitro analysis
topic chemical irrigation
herbal irrigation
sem
smear layer
url https://journals.lww.com/10.4103/jpbs.jpbs_371_25
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