Evaluating the Efficacy of Chemical and Herbal Endodontic Irrigants in Smear Layer Removal: An In-vitro Analysis

Aim: The current research is designed to analyze the smear layer (SL) removal efficacy of different endodontic irrigants via scanning electron microscope (SEM). Materials and Methods: Eighty extracted premolars were gathered and allocated into four groups (n = 20) based on the array of endodontic ir...

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Main Authors: Kanika Singh Dhull, Nayana Shriram Anasane, Sumit Singh, D. R. Mahesh, Vinay Rao, Meena Jain
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-05-01
Series:Journal of Pharmacy and Bioallied Sciences
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Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_371_25
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Summary:Aim: The current research is designed to analyze the smear layer (SL) removal efficacy of different endodontic irrigants via scanning electron microscope (SEM). Materials and Methods: Eighty extracted premolars were gathered and allocated into four groups (n = 20) based on the array of endodontic irrigants employed: Group 1: Normal saline (NS), Group 2: 17% EDTA (Ethylenediaminetetraacetic acid), Group 3: Neem leaf extract (NLE), and Group 4: Garlic solution (GS). SL elimination was evaluated beneath SEM at upper, intermediate, and apical levels of root canals. Results: The acquired data was evaluated using the non-parametric equivalent test. Groups 2 and 3 had the most effective SL clearance performance, followed by Group 4, while Group 1 had the lowest effectiveness at the upper, intermediate, and apical levels. An intergroup comparison revealed that Group 3 had successful SL reduction at the apical level. Conclusion: Group 3 outperformed the other groups in eliminating the SL at the upper, intermediate, and apical thirds.
ISSN:0976-4879
0975-7406