Efficacy and Safety of Poly-d,l-lactic Acid Delivered via a Transdermal Needle-free Microjet System for Enlarged Facial Pores
Summary:. Enlarged facial pores are a common cosmetic concern influenced by factors such as age, genetics, and sebum production. Traditional treatments such as topical retinoids, chemical peels, and laser therapies often yield variable results and may involve discomfort or multiple sessions. We repo...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer
2025-04-01
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| Series: | Plastic and Reconstructive Surgery, Global Open |
| Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006714 |
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| author | Suk Bae Seo, MD Hugues Cartier, MD Jovian Wan, MBChB Sebastien Garson, MD Kyu-Ho Yi, MD, PhD |
| author_facet | Suk Bae Seo, MD Hugues Cartier, MD Jovian Wan, MBChB Sebastien Garson, MD Kyu-Ho Yi, MD, PhD |
| author_sort | Suk Bae Seo, MD |
| collection | DOAJ |
| description | Summary:. Enlarged facial pores are a common cosmetic concern influenced by factors such as age, genetics, and sebum production. Traditional treatments such as topical retinoids, chemical peels, and laser therapies often yield variable results and may involve discomfort or multiple sessions. We report the case of a 41-year-old Korean woman treated for visibly enlarged pores using poly-d,l-lactic acid delivered via a needle-free microjet system. This system uses advanced electromagnetic technology to create high-pressure microjets that penetrate the skin’s outer layers, delivering therapeutic agents directly into the dermis. The patient underwent 5 monthly sessions, with significant improvements in pore size and skin texture observed within 4 weeks posttreatment. Clinical assessments showed a reduction in pore size from a baseline score of 6 to 3, sustained through 12 weeks posttreatment. The patient expressed satisfaction with the outcomes, reporting firmer, smoother skin with no adverse effects. Poly-d,l-lactic acid delivered via a microjet system was an effective, noninvasive treatment for enlarged facial pores in the treated patient. Further studies are needed to validate these findings and compare this approach with established therapies. |
| format | Article |
| id | doaj-art-bf0ebd788d11401d9dd6e8ae0ed3833c |
| institution | OA Journals |
| issn | 2169-7574 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Plastic and Reconstructive Surgery, Global Open |
| spelling | doaj-art-bf0ebd788d11401d9dd6e8ae0ed3833c2025-08-20T02:30:06ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742025-04-01134e671410.1097/GOX.0000000000006714202504000-00043Efficacy and Safety of Poly-d,l-lactic Acid Delivered via a Transdermal Needle-free Microjet System for Enlarged Facial PoresSuk Bae Seo, MD0Hugues Cartier, MD1Jovian Wan, MBChB2Sebastien Garson, MD3Kyu-Ho Yi, MD, PhD4From the * SeoAhSong Dermatologic Clinic, Seoul, Korea† Centre Médical Saint Jean, Arras, France‡ Medical Research Inc., Wonju, Korea§ Cabinet Médical, Senlis, FranceFrom the * SeoAhSong Dermatologic Clinic, Seoul, KoreaSummary:. Enlarged facial pores are a common cosmetic concern influenced by factors such as age, genetics, and sebum production. Traditional treatments such as topical retinoids, chemical peels, and laser therapies often yield variable results and may involve discomfort or multiple sessions. We report the case of a 41-year-old Korean woman treated for visibly enlarged pores using poly-d,l-lactic acid delivered via a needle-free microjet system. This system uses advanced electromagnetic technology to create high-pressure microjets that penetrate the skin’s outer layers, delivering therapeutic agents directly into the dermis. The patient underwent 5 monthly sessions, with significant improvements in pore size and skin texture observed within 4 weeks posttreatment. Clinical assessments showed a reduction in pore size from a baseline score of 6 to 3, sustained through 12 weeks posttreatment. The patient expressed satisfaction with the outcomes, reporting firmer, smoother skin with no adverse effects. Poly-d,l-lactic acid delivered via a microjet system was an effective, noninvasive treatment for enlarged facial pores in the treated patient. Further studies are needed to validate these findings and compare this approach with established therapies.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006714 |
| spellingShingle | Suk Bae Seo, MD Hugues Cartier, MD Jovian Wan, MBChB Sebastien Garson, MD Kyu-Ho Yi, MD, PhD Efficacy and Safety of Poly-d,l-lactic Acid Delivered via a Transdermal Needle-free Microjet System for Enlarged Facial Pores Plastic and Reconstructive Surgery, Global Open |
| title | Efficacy and Safety of Poly-d,l-lactic Acid Delivered via a Transdermal Needle-free Microjet System for Enlarged Facial Pores |
| title_full | Efficacy and Safety of Poly-d,l-lactic Acid Delivered via a Transdermal Needle-free Microjet System for Enlarged Facial Pores |
| title_fullStr | Efficacy and Safety of Poly-d,l-lactic Acid Delivered via a Transdermal Needle-free Microjet System for Enlarged Facial Pores |
| title_full_unstemmed | Efficacy and Safety of Poly-d,l-lactic Acid Delivered via a Transdermal Needle-free Microjet System for Enlarged Facial Pores |
| title_short | Efficacy and Safety of Poly-d,l-lactic Acid Delivered via a Transdermal Needle-free Microjet System for Enlarged Facial Pores |
| title_sort | efficacy and safety of poly d l lactic acid delivered via a transdermal needle free microjet system for enlarged facial pores |
| url | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006714 |
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