Effect of Application of Different Exercise Intensities on Vitamin D and Parathormone in Children with Down’s Syndrome

Background. Children with Down’s syndrome are more liable to vitamin D deficiency. Treating this deficiency with supplements is associated with the risk of intoxication. Aim. The study is aimed at comparing the effect of two exercise intensities on the modulation of vitamin D and parathormone levels...

Full description

Saved in:
Bibliographic Details
Main Authors: Hatem H. Allam, Alaa Shafie, Amal F. Gharib, Ahmad El Askary, Mazen Almehmadi, Tarek Alsayad, Ahmed M. Alziyadi, Lamiaa K. Elsayyad
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Applied Bionics and Biomechanics
Online Access:http://dx.doi.org/10.1155/2021/7424857
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849685472637353984
author Hatem H. Allam
Alaa Shafie
Amal F. Gharib
Ahmad El Askary
Mazen Almehmadi
Tarek Alsayad
Ahmed M. Alziyadi
Lamiaa K. Elsayyad
author_facet Hatem H. Allam
Alaa Shafie
Amal F. Gharib
Ahmad El Askary
Mazen Almehmadi
Tarek Alsayad
Ahmed M. Alziyadi
Lamiaa K. Elsayyad
author_sort Hatem H. Allam
collection DOAJ
description Background. Children with Down’s syndrome are more liable to vitamin D deficiency. Treating this deficiency with supplements is associated with the risk of intoxication. Aim. The study is aimed at comparing the effect of two exercise intensities on the modulation of vitamin D and parathormone levels in children with DS. Methods. Forty-four DS male children aged from 8 to 12 years participated in the study. They were assigned randomly into two equal groups. Group I received high-intensity treadmill aerobic exercises, and group II received moderate-intensity T-AE, three times per week for three months. The blood samples were collected from both groups before the intervention, after one month of intervention, then after three months of intervention to assess serum 25(OH)D and PTH levels. Results. Repeated measure MANOVA revealed that the high-intensity T-AE induced a significant increase in 25(OH)D after one month and after three months while it significantly decreased PTH only after three months. Moderate-intensity T-AE had a nonsignificant effect on both hormones. Conclusion. The current study concluded that the high-intensity T-AE improved both vitamin D and parathormone serum levels after three months of intervention.
format Article
id doaj-art-bf0c7bea3f6e431cb0dd5c4b59fa2edd
institution DOAJ
issn 1754-2103
language English
publishDate 2021-01-01
publisher Wiley
record_format Article
series Applied Bionics and Biomechanics
spelling doaj-art-bf0c7bea3f6e431cb0dd5c4b59fa2edd2025-08-20T03:23:07ZengWileyApplied Bionics and Biomechanics1754-21032021-01-01202110.1155/2021/7424857Effect of Application of Different Exercise Intensities on Vitamin D and Parathormone in Children with Down’s SyndromeHatem H. Allam0Alaa Shafie1Amal F. Gharib2Ahmad El Askary3Mazen Almehmadi4Tarek Alsayad5Ahmed M. Alziyadi6Lamiaa K. Elsayyad7Physical Therapy DepartmentDepartment of Clinical Laboratory SciencesDepartment of Clinical Laboratory SciencesDepartment of Clinical Laboratory SciencesDepartment of Clinical Laboratory SciencesLecturer of PediatricsAcademic Affairs DirectorPhysical Therapy DepartmentBackground. Children with Down’s syndrome are more liable to vitamin D deficiency. Treating this deficiency with supplements is associated with the risk of intoxication. Aim. The study is aimed at comparing the effect of two exercise intensities on the modulation of vitamin D and parathormone levels in children with DS. Methods. Forty-four DS male children aged from 8 to 12 years participated in the study. They were assigned randomly into two equal groups. Group I received high-intensity treadmill aerobic exercises, and group II received moderate-intensity T-AE, three times per week for three months. The blood samples were collected from both groups before the intervention, after one month of intervention, then after three months of intervention to assess serum 25(OH)D and PTH levels. Results. Repeated measure MANOVA revealed that the high-intensity T-AE induced a significant increase in 25(OH)D after one month and after three months while it significantly decreased PTH only after three months. Moderate-intensity T-AE had a nonsignificant effect on both hormones. Conclusion. The current study concluded that the high-intensity T-AE improved both vitamin D and parathormone serum levels after three months of intervention.http://dx.doi.org/10.1155/2021/7424857
spellingShingle Hatem H. Allam
Alaa Shafie
Amal F. Gharib
Ahmad El Askary
Mazen Almehmadi
Tarek Alsayad
Ahmed M. Alziyadi
Lamiaa K. Elsayyad
Effect of Application of Different Exercise Intensities on Vitamin D and Parathormone in Children with Down’s Syndrome
Applied Bionics and Biomechanics
title Effect of Application of Different Exercise Intensities on Vitamin D and Parathormone in Children with Down’s Syndrome
title_full Effect of Application of Different Exercise Intensities on Vitamin D and Parathormone in Children with Down’s Syndrome
title_fullStr Effect of Application of Different Exercise Intensities on Vitamin D and Parathormone in Children with Down’s Syndrome
title_full_unstemmed Effect of Application of Different Exercise Intensities on Vitamin D and Parathormone in Children with Down’s Syndrome
title_short Effect of Application of Different Exercise Intensities on Vitamin D and Parathormone in Children with Down’s Syndrome
title_sort effect of application of different exercise intensities on vitamin d and parathormone in children with down s syndrome
url http://dx.doi.org/10.1155/2021/7424857
work_keys_str_mv AT hatemhallam effectofapplicationofdifferentexerciseintensitiesonvitamindandparathormoneinchildrenwithdownssyndrome
AT alaashafie effectofapplicationofdifferentexerciseintensitiesonvitamindandparathormoneinchildrenwithdownssyndrome
AT amalfgharib effectofapplicationofdifferentexerciseintensitiesonvitamindandparathormoneinchildrenwithdownssyndrome
AT ahmadelaskary effectofapplicationofdifferentexerciseintensitiesonvitamindandparathormoneinchildrenwithdownssyndrome
AT mazenalmehmadi effectofapplicationofdifferentexerciseintensitiesonvitamindandparathormoneinchildrenwithdownssyndrome
AT tarekalsayad effectofapplicationofdifferentexerciseintensitiesonvitamindandparathormoneinchildrenwithdownssyndrome
AT ahmedmalziyadi effectofapplicationofdifferentexerciseintensitiesonvitamindandparathormoneinchildrenwithdownssyndrome
AT lamiaakelsayyad effectofapplicationofdifferentexerciseintensitiesonvitamindandparathormoneinchildrenwithdownssyndrome