New Functional Fermented Mare’s Milk Product: Biological Assessment in vivo
The growing consumer interest in healthy foods increases the demand for new functional products. Mare’s milk and its products possess some unique nutritional properties. This article introduces a new fermented functional food that combines mare’s milk, cow’s milk, lactic acid, and probiotic microorg...
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| Format: | Article |
| Language: | English |
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Kemerovo State University
2024-12-01
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| Series: | Техника и технология пищевых производств |
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| Online Access: | https://fptt.ru/en/issues/23109/23120/ |
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| author | Elena S. Simonenko Sergey V. Simonenko Anna V. Begunova Andrey N. Petrov Elena S. Semenovа |
| author_facet | Elena S. Simonenko Sergey V. Simonenko Anna V. Begunova Andrey N. Petrov Elena S. Semenovа |
| author_sort | Elena S. Simonenko |
| collection | DOAJ |
| description | The growing consumer interest in healthy foods increases the demand for new functional products. Mare’s milk and its products possess some unique nutritional properties. This article introduces a new fermented functional food that combines mare’s milk, cow’s milk, lactic acid, and probiotic microorganisms.
The research featured fermented milk products based on mare’s milk, cow’s milk, and their mixes. The preclinical studies involved clinically healthy female mice (C57BL/6J). The biochemical analysis of blood plasma was performed on a BioChem FC-360 automatic analyzer while the histological preparations relied on an AxioImaiger A1 light microscope. The quantitative assessment employed the ImageJ software (USA).
The mice obtained the so-called Western diet and the experimental product. Their low-density lipoprotein cholesterol (LDL-C) decreased by 254-30.0% while the high-density lipoprotein cholesterol (HDL-C) went up. The mice that were given the experimental product demonstrated lower creatinine, urea, and alanine aminotransferase activity in the blood plasma, which indicated a certain hepatoprotective effect. The experimental product caused a statistically significant decrease in granulocytes, i.e., the microbiome had an anti-inflammatory effect on the gut microbiota, which, in its turn, affected the cytokine expression.
The new product demonstrated strong biological activity, which rendered it functional properties. Further research will determine the effect of fermented milk products as part of a comprehensive diet on non-alcoholic fatty liver disease. |
| format | Article |
| id | doaj-art-bf0b68c2c98546da9e40c4b77b104ee5 |
| institution | DOAJ |
| issn | 2074-9414 2313-1748 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Kemerovo State University |
| record_format | Article |
| series | Техника и технология пищевых производств |
| spelling | doaj-art-bf0b68c2c98546da9e40c4b77b104ee52025-08-20T03:01:07ZengKemerovo State UniversityТехника и технология пищевых производств2074-94142313-17482024-12-0154467568610.21603/2074-9414-2024-4-2535New Functional Fermented Mare’s Milk Product: Biological Assessment in vivoElena S. Simonenko0https://orcid.org/0000-0002-2878-8069Sergey V. Simonenko1https://orcid.org/0000-0002-6999-5048Anna V. Begunova2https://orcid.org/0000-0002-5360-8955Andrey N. Petrov3https://orcid.org/0000-0001-9879-482XElena S. Semenovа4https://orcid.org/0000-0003-3848-7478All-Russian Research Institute of Baby Nutrition, Istra, RussiaAll-Russian Research Institute of Baby Nutrition, Istra, RussiaAll-Russian Research Institute of Baby Nutrition, Istra, RussiaAll-Russian Scientific Research Institute of Dairy Industry, Moscow, RussiaAll-Russian Research Institute of Baby Nutrition, Istra, RussiaThe growing consumer interest in healthy foods increases the demand for new functional products. Mare’s milk and its products possess some unique nutritional properties. This article introduces a new fermented functional food that combines mare’s milk, cow’s milk, lactic acid, and probiotic microorganisms. The research featured fermented milk products based on mare’s milk, cow’s milk, and their mixes. The preclinical studies involved clinically healthy female mice (C57BL/6J). The biochemical analysis of blood plasma was performed on a BioChem FC-360 automatic analyzer while the histological preparations relied on an AxioImaiger A1 light microscope. The quantitative assessment employed the ImageJ software (USA). The mice obtained the so-called Western diet and the experimental product. Their low-density lipoprotein cholesterol (LDL-C) decreased by 254-30.0% while the high-density lipoprotein cholesterol (HDL-C) went up. The mice that were given the experimental product demonstrated lower creatinine, urea, and alanine aminotransferase activity in the blood plasma, which indicated a certain hepatoprotective effect. The experimental product caused a statistically significant decrease in granulocytes, i.e., the microbiome had an anti-inflammatory effect on the gut microbiota, which, in its turn, affected the cytokine expression. The new product demonstrated strong biological activity, which rendered it functional properties. Further research will determine the effect of fermented milk products as part of a comprehensive diet on non-alcoholic fatty liver disease.https://fptt.ru/en/issues/23109/23120/fermented milk productmare’s milkcow’s milkprobioticsbiological effects |
| spellingShingle | Elena S. Simonenko Sergey V. Simonenko Anna V. Begunova Andrey N. Petrov Elena S. Semenovа New Functional Fermented Mare’s Milk Product: Biological Assessment in vivo Техника и технология пищевых производств fermented milk product mare’s milk cow’s milk probiotics biological effects |
| title | New Functional Fermented Mare’s Milk Product: Biological Assessment in vivo |
| title_full | New Functional Fermented Mare’s Milk Product: Biological Assessment in vivo |
| title_fullStr | New Functional Fermented Mare’s Milk Product: Biological Assessment in vivo |
| title_full_unstemmed | New Functional Fermented Mare’s Milk Product: Biological Assessment in vivo |
| title_short | New Functional Fermented Mare’s Milk Product: Biological Assessment in vivo |
| title_sort | new functional fermented mare s milk product biological assessment in vivo |
| topic | fermented milk product mare’s milk cow’s milk probiotics biological effects |
| url | https://fptt.ru/en/issues/23109/23120/ |
| work_keys_str_mv | AT elenassimonenko newfunctionalfermentedmaresmilkproductbiologicalassessmentinvivo AT sergeyvsimonenko newfunctionalfermentedmaresmilkproductbiologicalassessmentinvivo AT annavbegunova newfunctionalfermentedmaresmilkproductbiologicalassessmentinvivo AT andreynpetrov newfunctionalfermentedmaresmilkproductbiologicalassessmentinvivo AT elenassemenova newfunctionalfermentedmaresmilkproductbiologicalassessmentinvivo |