Endocervical Adenocarcinoma as a Secondary Malignancy in a Patient Treated for Non-Hodgkin's Lymphoma: A Case Report with Review of Literature

Secondary malignancy can arise in patients with non-Hodgkin's lymphoma (NHL) on long follow-up. The risk of developing secondary malignancies is increased in NHL survivors, as compared to normal population and varies according to age, gender, and treatment modality. The nature of solid organ ma...

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Bibliographic Details
Main Authors: Garima Dhull, Minakshi Bhardwaj, Stuti Gupta, Mukta Pujani, Varsha Chauhan, Neha Garg, J.C Sharma, Sunita Malik
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd.
Series:Indian Journal of Medical and Paediatric Oncology
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0045-1810067
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Summary:Secondary malignancy can arise in patients with non-Hodgkin's lymphoma (NHL) on long follow-up. The risk of developing secondary malignancies is increased in NHL survivors, as compared to normal population and varies according to age, gender, and treatment modality. The nature of solid organ malignancy in order of frequency includes lung cancer followed by prostate, bladder, colon, breast, etc. Gynecological malignancy occurring in an NHL survivor is an extremely rare phenomenon with a low observed/expected ratio (0.89–0.93) as compared to other solid tumors. We hereby report a case of endocervical adenocarcinoma arising in a 51-year-old female patient who was a known treated case of NHL. This case highlights the fact that chemotherapy-induced atypia may mimic malignancy as well as the rare occurrence of gynecological cancers as a secondary malignancy in patients with NHL.
ISSN:0971-5851
0975-2129