Laboratory diagnosis of emerging human infections by SARS-COVID-19: Prevalence and challenges
The COVID-19 pandemic has created a global storm in the world, and nations worldwide are skirmishing with this unprecedented health crisis. The outbreak of Corona Virus Disease19 (COVID-19), caused by Severe Acute Respiratory Syndrome Corona Virus - 2 (SARSCoV-2), had a significant impact on the he...
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| Format: | Article |
| Language: | English |
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ResearchersLinks, Ltd
2022-06-01
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| Series: | Novel Research in Microbiology Journal |
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| Online Access: | https://nrmj.journals.ekb.eg/article_244415_aeaa499cc4e42efb4093e1002fbfa510.pdf |
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| _version_ | 1849685767558791168 |
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| author | Soumya Nigam Urvashi Vijay Bhumandeep Kour |
| author_facet | Soumya Nigam Urvashi Vijay Bhumandeep Kour |
| author_sort | Soumya Nigam |
| collection | DOAJ |
| description | The COVID-19 pandemic has created a global storm in the world, and nations worldwide
are skirmishing with this unprecedented health crisis. The outbreak of Corona Virus Disease19 (COVID-19), caused by Severe Acute Respiratory Syndrome Corona Virus - 2 (SARSCoV-2), had a significant impact on the healthcare system, especially in the clinical
microbiology laboratories worldwide. The choice of a correct anatomical site for good samples
collections with the proper precautions is essential for prompt and accurate diagnosis of
COVID-19. This review aimed to cover the challenges faced during the choice of appropriate
sample collection sites, transport and tests for detection of SARS-CoV-2 infection. The
diagnosis tests of COVID-19 can be divided into direct, indirect and complementary tests. In
the direct tests, Real-time polymerase chain reaction (RT-PCR) assays are the molecular tests
of choice for the diagnosis of COVID-19. The remaining direct tests include GeneXpert and
TrueNAT assays. In the indirect testing's; antigen-antibody-based techniques are
recommended for surveillance of the disease, which may help to formulate the control
measures. These tests not only help in assessing the disease severity, but also they benefit in
evaluating the prognosis and management strategies. |
| format | Article |
| id | doaj-art-befb76f121154724a1f854df79da0da1 |
| institution | DOAJ |
| issn | 2537-0286 2537-0294 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | ResearchersLinks, Ltd |
| record_format | Article |
| series | Novel Research in Microbiology Journal |
| spelling | doaj-art-befb76f121154724a1f854df79da0da12025-08-20T03:22:59ZengResearchersLinks, LtdNovel Research in Microbiology Journal2537-02862537-02942022-06-01631601161310.21608/nrmj.2022.244415Laboratory diagnosis of emerging human infections by SARS-COVID-19: Prevalence and challengesSoumya Nigam0 Urvashi Vijay1Bhumandeep Kour2Department of Microbiology and Immunology, SMS Medical College and Attached Hospitals, Jaipur -302001, Rajasthan, IndiaMulti-Disciplinary Research Unit, SMS Medical College and Attached Hospitals, Jaipur - 302001, Rajasthan, IndiaDepartment of Biotechnology, School of Engineering and Bioscience, Lovely Professional University, Punjab-144402, Punjab, IndiaThe COVID-19 pandemic has created a global storm in the world, and nations worldwide are skirmishing with this unprecedented health crisis. The outbreak of Corona Virus Disease19 (COVID-19), caused by Severe Acute Respiratory Syndrome Corona Virus - 2 (SARSCoV-2), had a significant impact on the healthcare system, especially in the clinical microbiology laboratories worldwide. The choice of a correct anatomical site for good samples collections with the proper precautions is essential for prompt and accurate diagnosis of COVID-19. This review aimed to cover the challenges faced during the choice of appropriate sample collection sites, transport and tests for detection of SARS-CoV-2 infection. The diagnosis tests of COVID-19 can be divided into direct, indirect and complementary tests. In the direct tests, Real-time polymerase chain reaction (RT-PCR) assays are the molecular tests of choice for the diagnosis of COVID-19. The remaining direct tests include GeneXpert and TrueNAT assays. In the indirect testing's; antigen-antibody-based techniques are recommended for surveillance of the disease, which may help to formulate the control measures. These tests not only help in assessing the disease severity, but also they benefit in evaluating the prognosis and management strategies. https://nrmj.journals.ekb.eg/article_244415_aeaa499cc4e42efb4093e1002fbfa510.pdfcovid-19real-time polymerase chain reaction (rt-pcr)sars-cov-2molecular tests |
| spellingShingle | Soumya Nigam Urvashi Vijay Bhumandeep Kour Laboratory diagnosis of emerging human infections by SARS-COVID-19: Prevalence and challenges Novel Research in Microbiology Journal covid-19 real-time polymerase chain reaction (rt-pcr) sars-cov-2 molecular tests |
| title | Laboratory diagnosis of emerging human infections by SARS-COVID-19: Prevalence and challenges |
| title_full | Laboratory diagnosis of emerging human infections by SARS-COVID-19: Prevalence and challenges |
| title_fullStr | Laboratory diagnosis of emerging human infections by SARS-COVID-19: Prevalence and challenges |
| title_full_unstemmed | Laboratory diagnosis of emerging human infections by SARS-COVID-19: Prevalence and challenges |
| title_short | Laboratory diagnosis of emerging human infections by SARS-COVID-19: Prevalence and challenges |
| title_sort | laboratory diagnosis of emerging human infections by sars covid 19 prevalence and challenges |
| topic | covid-19 real-time polymerase chain reaction (rt-pcr) sars-cov-2 molecular tests |
| url | https://nrmj.journals.ekb.eg/article_244415_aeaa499cc4e42efb4093e1002fbfa510.pdf |
| work_keys_str_mv | AT soumyanigam laboratorydiagnosisofemerginghumaninfectionsbysarscovid19prevalenceandchallenges AT urvashivijay laboratorydiagnosisofemerginghumaninfectionsbysarscovid19prevalenceandchallenges AT bhumandeepkour laboratorydiagnosisofemerginghumaninfectionsbysarscovid19prevalenceandchallenges |