Laboratory diagnosis of emerging human infections by SARS-COVID-19: Prevalence and challenges
The COVID-19 pandemic has created a global storm in the world, and nations worldwide are skirmishing with this unprecedented health crisis. The outbreak of Corona Virus Disease19 (COVID-19), caused by Severe Acute Respiratory Syndrome Corona Virus - 2 (SARSCoV-2), had a significant impact on the he...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
ResearchersLinks, Ltd
2022-06-01
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| Series: | Novel Research in Microbiology Journal |
| Subjects: | |
| Online Access: | https://nrmj.journals.ekb.eg/article_244415_aeaa499cc4e42efb4093e1002fbfa510.pdf |
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| Summary: | The COVID-19 pandemic has created a global storm in the world, and nations worldwide
are skirmishing with this unprecedented health crisis. The outbreak of Corona Virus Disease19 (COVID-19), caused by Severe Acute Respiratory Syndrome Corona Virus - 2 (SARSCoV-2), had a significant impact on the healthcare system, especially in the clinical
microbiology laboratories worldwide. The choice of a correct anatomical site for good samples
collections with the proper precautions is essential for prompt and accurate diagnosis of
COVID-19. This review aimed to cover the challenges faced during the choice of appropriate
sample collection sites, transport and tests for detection of SARS-CoV-2 infection. The
diagnosis tests of COVID-19 can be divided into direct, indirect and complementary tests. In
the direct tests, Real-time polymerase chain reaction (RT-PCR) assays are the molecular tests
of choice for the diagnosis of COVID-19. The remaining direct tests include GeneXpert and
TrueNAT assays. In the indirect testing's; antigen-antibody-based techniques are
recommended for surveillance of the disease, which may help to formulate the control
measures. These tests not only help in assessing the disease severity, but also they benefit in
evaluating the prognosis and management strategies. |
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| ISSN: | 2537-0286 2537-0294 |