CLINICAL APPLICATION OF BONE MORPHOGENETIC PROTEIN ON FRACTURE HEALING PROCESS
Delayed union or non-union often occurs in bone healing fracture process. The clinical application of Bone Morphogenetic Proteins (BMPs) has helped an increasing number of patients achieve bone regeneration in clinical area lacking simple solutions for difficult bone healing situations. Many researc...
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| Format: | Article |
| Language: | English |
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Universitas Airlangga
2019-12-01
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| Series: | Journal Orthopaedi and Traumatology Surabaya |
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| Online Access: | https://e-journal.unair.ac.id/JOINTS/article/view/9168 |
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| _version_ | 1823856528609771520 |
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| author | Riko Febrian Kunta Adjie |
| author_facet | Riko Febrian Kunta Adjie |
| author_sort | Riko Febrian Kunta Adjie |
| collection | DOAJ |
| description | Delayed union or non-union often occurs in bone healing fracture process. The clinical application of Bone Morphogenetic Proteins (BMPs) has helped an increasing number of patients achieve bone regeneration in clinical area lacking simple solutions for difficult bone healing situations. Many researches has proved that BMPs improved fracture healing regeneration. In this review article, introduction and current clinical issues are summarized on efficacy and function of BMPs. Currently, rhBMP-2 and rhBMP-7 have shown clinical significance but other subfamily members of BMPs still lacked of evidence. |
| format | Article |
| id | doaj-art-befb045f0be54f02813cfd24189f7bf7 |
| institution | Kabale University |
| issn | 2722-712X 2460-8742 |
| language | English |
| publishDate | 2019-12-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Journal Orthopaedi and Traumatology Surabaya |
| spelling | doaj-art-befb045f0be54f02813cfd24189f7bf72025-02-12T07:29:36ZengUniversitas AirlanggaJournal Orthopaedi and Traumatology Surabaya2722-712X2460-87422019-12-0162485410.20473/joints.v6i2.2017.48-547264CLINICAL APPLICATION OF BONE MORPHOGENETIC PROTEIN ON FRACTURE HEALING PROCESSRiko Febrian Kunta Adjie0Dokter Umum Internship RSUD Ben MboiDelayed union or non-union often occurs in bone healing fracture process. The clinical application of Bone Morphogenetic Proteins (BMPs) has helped an increasing number of patients achieve bone regeneration in clinical area lacking simple solutions for difficult bone healing situations. Many researches has proved that BMPs improved fracture healing regeneration. In this review article, introduction and current clinical issues are summarized on efficacy and function of BMPs. Currently, rhBMP-2 and rhBMP-7 have shown clinical significance but other subfamily members of BMPs still lacked of evidence.https://e-journal.unair.ac.id/JOINTS/article/view/9168bone morphogenetic proteinfracturegrowth factor bonehealing |
| spellingShingle | Riko Febrian Kunta Adjie CLINICAL APPLICATION OF BONE MORPHOGENETIC PROTEIN ON FRACTURE HEALING PROCESS Journal Orthopaedi and Traumatology Surabaya bone morphogenetic protein fracture growth factor bone healing |
| title | CLINICAL APPLICATION OF BONE MORPHOGENETIC PROTEIN ON FRACTURE HEALING PROCESS |
| title_full | CLINICAL APPLICATION OF BONE MORPHOGENETIC PROTEIN ON FRACTURE HEALING PROCESS |
| title_fullStr | CLINICAL APPLICATION OF BONE MORPHOGENETIC PROTEIN ON FRACTURE HEALING PROCESS |
| title_full_unstemmed | CLINICAL APPLICATION OF BONE MORPHOGENETIC PROTEIN ON FRACTURE HEALING PROCESS |
| title_short | CLINICAL APPLICATION OF BONE MORPHOGENETIC PROTEIN ON FRACTURE HEALING PROCESS |
| title_sort | clinical application of bone morphogenetic protein on fracture healing process |
| topic | bone morphogenetic protein fracture growth factor bone healing |
| url | https://e-journal.unair.ac.id/JOINTS/article/view/9168 |
| work_keys_str_mv | AT rikofebriankuntaadjie clinicalapplicationofbonemorphogeneticproteinonfracturehealingprocess |