A rare IDH-Mutant glioma case: insights from single-cell transcriptomic analysis of tumor recurrences

A rare IDH-Mutant glioma case: insights from single-cell transcriptomic analysis of tumor recurrences

Abstract Background Isocitrate dehydrogenase (IDH) mutations are associated with better prognosis and longer survival in gliomas. In contrast, multifocal glioma is a rare intracranial tumor, primarily affecting middle-aged and elderly individuals. While recurrence is common due to the complex tumor...

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Bibliographic Details
Main Authors: Wen Li, Yuanshuai Zhou, Shaheryar Shafi, Jun Dong, Minxuan Sun
Format: Article
Language:English
Published: BMC 2025-07-01
Series:World Journal of Surgical Oncology
Subjects:
Recurrent glioma
Multifocal glioma
scRNA-seq
Oligodendrocyte precursor cells
Oligodendrocytes
Online Access:https://doi.org/10.1186/s12957-025-03913-z
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